Application
Fig1: Western blot analysis of UFO on recombinant protein lysate using anti-UFO antibody at 1/20,000 dilution.Application
Fig2: ICC staining UFO (green) in SW480 cells. The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.| Product Name | UFO [C4-A8] |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | Adhesion related kinase antibody AI323647 antibody Ark antibody Axl antibody AXL oncogene antibody AXL receptor tyrosine kinase antibody AXL transforming gene antibody AXL transforming sequence/gene antibody EC 2.7.10.1 antibody JTK11 antibody Oncogene AXL antibody Tyro7 antibody Tyrosine protein kinase receptor UFO antibody Tyrosine-protein kinase receptor UFO antibody UFO antibody UFO_HUMAN antibody |
| Product description | Tyrosine-protein kinase receptor UFO is an enzyme that in humans is encoded by the AXL gene. The protein encoded by this gene is a member of the receptor tyrosine kinase subfamily. Although it is similar to other receptor tyrosine kinases, the Axl protein represents a unique structure of the extracellular region that juxtaposes IgL and FNIII repeats. It transduces signals from the extracellular matrix into the cytoplasm by binding growth factors like vitamin K-dependent protein growth-arrest-specific gene 6. It is involved in the stimulation of cell proliferation. This receptor can also mediate cell aggregation by homophilic binding. Axl is a chronic myelogenous leukemia-associated oncogene and also associated with colon cancer and melanoma. AXL receptor tyrosine kinase has been shown to interact with TENC1.Axl is an essential epithelial-to-mesenchymal transition-induced regulator of breast cancer metastasis and patient survival. |
| Immunogen | Recombinant protein within human UFO 1-150 aa. |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG1 |
| Host Species | Mouse |
| Tested Applications | WBICC |
| WB:1:250~1:1000 ICC:1:100~1:200 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|
| Species Reactivity | Human |
| Concentration | 2mg/ml |
| Alternative Names | Adhesion related kinase antibody AI323647 antibody Ark antibody Axl antibody AXL oncogene antibody AXL receptor tyrosine kinase antibody AXL transforming gene antibody AXL transforming sequence/gene antibody EC 2.7.10.1 antibody JTK11 antibody Oncogene AXL antibody Tyro7 antibody Tyrosine protein kinase receptor UFO antibody Tyrosine-protein kinase receptor UFO antibody UFO antibody UFO_HUMAN antibody |
|---|---|
| Molecular Weight(MW) | 98 kDa |
| Cellular Localization | Cell membrane |
| SwissProt ID | P30530 |
|---|
Application
Fig1: Western blot analysis of UFO on recombinant protein lysate using anti-UFO antibody at 1/20,000 dilution.
Application
Fig2: ICC staining UFO (green) in SW480 cells. The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.| Positive Control | Recombinant protein lysate, SW480. |
|---|---|
| Application Notes | WB:1:250~1:1000 ICC:1:100~1:200 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4℃ after thawing. Aliquot store at -20℃. Avoid repeated freeze / thaw cycles. |
| Storage Buffer | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
