Application
Fig1: Western blot analysis on cell lysates using anti- PODXL Mouse mAb.| Product Name | PODXL [D0-E8] |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | GCTM-2 antigen antibody Gp2 antibody Gp200 antibody MGC138240 antibody PC antibody PCLP antibody PCLP-1 antibody PCLP1 antibody Pcx antibody Podocalyxin antibody Podocalyxin like antibody Podocalyxin like protein antibody Podocalyxin-like protein 1 antibody Podxl antibody PODXL_HUMAN antibody |
| Product description | Podocalyxin, a sialoglycoprotein, is thought to be the major constituent of the glycocalyx of podocytes. It is a member of the CD34 family of transmembrane sialomucins. It is involved in the regulation of both adhesion and cell morphology and cancer progression. It functions as an anti-adhesive molecule that maintains an open filtration pathway between neighboring foot processes in the podocyte by charge repulsion. Podocalyxin acts as a pro-adhesive molecule, enhancing the adherence of cells to immobilized ligands, increasing the rate of migration and cell-cell contacts in an integrin-dependent manner. Sialylated, O-glycosylated glycoforms of podocalyxin expressed by colon carcinoma cells possess L-selectin and E-selectin binding activity, and may be pivotal to the metastatic spread of colon carcinoma cells |
| Immunogen | recombinant protein |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG1 |
| Host Species | Mouse |
| Tested Applications | WB |
| WB 1:2,000-1:5,000: |
|
| Species Reactivity | Human |
| Concentration | 2mg/ml |
| Alternative Names | GCTM-2 antigen antibody Gp2 antibody Gp200 antibody MGC138240 antibody PC antibody PCLP antibody PCLP-1 antibody PCLP1 antibody Pcx antibody Podocalyxin antibody Podocalyxin like antibody Podocalyxin like protein antibody Podocalyxin-like protein 1 antibody Podxl antibody PODXL_HUMAN antibody |
|---|---|
| Molecular Weight(MW) | 58kDa |
| Cellular Localization | Apical cell membrane |
| SwissProt ID | O00592 |
|---|
Application
Fig1: Western blot analysis on cell lysates using anti- PODXL Mouse mAb.| Positive Control | HCT116, HT29, SW480 |
|---|---|
| Application Notes | WB 1:2,000-1:5,000: |
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles. |
| Storage Buffer | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
