Application
Fig1: ICC staining PTPRB in F9 cells (red). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS and counterstained with DAPI in order to highlight the nucleus (blue).| Product Name | PTPRB [2-A2] |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | HPTP BETA antibody HPTPB antibody Phosphacan receptor type B antibody Protein tyrosine phosphatase receptor type B antibody Protein-tyrosine phosphatase beta antibody PTPB antibody Ptprb antibody PTPRB_HUMAN antibody R PTP BETA antibody R-PTP-beta antibody Receptor-type tyrosine-protein phosphatase beta antibody RPTPB antibody Vascular endothelial protein tyrosine phosphatase antibody VE-PTP antibody |
| Product description | DNA (cytosine-5)-methyltransferase 3-like is an enzyme that in humans is encoded by the DNMT3L Receptor-type tyrosine-protein phosphatase beta is an enzyme that in humans is encoded by the PTPRB gene. The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. PTPRB plays an important role in blood vessel remodeling and angiogenesis. It is not necessary for the initial formation of blood vessels, but is essential for their maintenance and remodeling. PTPRB can induce dephosphorylation of TEK/TIE2, CDH5/VE-cadherin and KDR/VEGFR-2. It regulates angiopoietin-TIE2 signaling in endothelial cells. |
| Immunogen | recombinant protein |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG2a |
| Host Species | Mouse |
| Tested Applications | ICC |
| ICC:1:1,000 |
|
| Species Reactivity | HumanMouse |
| Concentration | 2mg/ml |
| Alternative Names | HPTP BETA antibody HPTPB antibody Phosphacan receptor type B antibody Protein tyrosine phosphatase receptor type B antibody Protein-tyrosine phosphatase beta antibody PTPB antibody Ptprb antibody PTPRB_HUMAN antibody R PTP BETA antibody R-PTP-beta antibody Receptor-type tyrosine-protein phosphatase beta antibody RPTPB antibody Vascular endothelial protein tyrosine phosphatase antibody VE-PTP antibody |
|---|---|
| Molecular Weight(MW) | 224kDa |
| Cellular Localization | Membrane |
| SwissProt ID | P23467 |
|---|
Application
Fig1: ICC staining PTPRB in F9 cells (red). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS and counterstained with DAPI in order to highlight the nucleus (blue).| Positive Control | F9 |
|---|---|
| Application Notes | ICC:1:1,000 |
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles. |
| Storage Buffer | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
