Application
Fig1: Western blot analysis on D3 cell lysates using anti- UTF1 mouse mAb.Application
Fig2: ICC staining UTF1 in D3 cells (red). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.| Product Name | UTF1 [E0-F4] |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | hUTF 1 antibody hUTF1 antibody Undifferentiated embryonic cell transcription factor 1 antibody UTF 1 antibody UTF1 antibody UTF1_HUMAN antibody |
| Product description | Undifferentiated embryonic cell transcription factor 1 is a protein in humans that is encoded by the UTF1 gene. UTF1, first reported in 1998, is expressed in pluripotent cells including embryonic stem cells and embryonic carcinoma cells. Its expression is rapidly reduced upon differentiation. UTF1 protein is localized to the cell nucleus, where it functions to regulate the pluripotent chromatin state and buffer mRNA levels by promoting degradation of mRNA. Aberrant expression of UTF1 has also been reported in cervical cancer cells, where the UTF1 gene promoter loses methylation and becomes abnormally expressed compared to normal cervical cells. |
| Immunogen | peptide |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG2b |
| Host Species | Mouse |
| Tested Applications | WBICC |
| WB:1:500-1:1,000 ICC:1:500-1:1,000 |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 2mg/ml |
| Alternative Names | hUTF 1 antibody hUTF1 antibody Undifferentiated embryonic cell transcription factor 1 antibody UTF 1 antibody UTF1 antibody UTF1_HUMAN antibody |
|---|---|
| Molecular Weight(MW) | 36-50 kDa |
| Cellular Localization | Nucleus |
| SwissProt ID | Q5T230 |
|---|
Application
Fig1: Western blot analysis on D3 cell lysates using anti- UTF1 mouse mAb.
Application
Fig2: ICC staining UTF1 in D3 cells (red). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.| Positive Control | D3 |
|---|---|
| Application Notes | WB:1:500-1:1,000 ICC:1:500-1:1,000 |
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles. |
| Storage Buffer | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
