Application
Fig1: Western blot analysis of Cathepsin B on SW480 cell lysate using anti-Cathepsin B antibody at 1/5,000 dilution.Application
Fig2: ICC staining Cathepsin B (red) in HepG2 cells. Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.Application
Fig3: Western blot analysis of Cathepsin B on hybrid fish (crucian-carp) brain tissue lysate using anti-Cathepsin B antibody at 1/500 dilution.| Product Name | Cathepsin B [J11-A11] |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | Amyloid precursor protein secretase antibody APP secretase antibody APPS antibody CATB_HUMAN antibody Cathepsin B heavy chain antibody Cathepsin B1 antibody CathepsinB antibody CPSB antibody CTSB antibody cysteine protease antibody OTTHUMP00000116009 antibody OTTHUMP00000229510 antibody OTTHUMP00000229511 antibody OTTHUMP00000229512 antibody OTTHUMP00000229514 antibody OTTHUMP00000229515 antibody OTTHUMP00000229516 antibody Preprocathepsin B antibody |
| Product description | Cathepsin B is an enzymatic protein belonging to the peptidase (or protease) families. In humans, it is coded by the CTSB gene. A wide array of diseases results in elevated levels of cathepsin B, which causes numerous pathological processes including cell death, inflammation, and production of toxic peptides. Focusing on neurological diseases, cathepsin B gene knockout studies in an epileptic rodent model have shown cathepsin B causes a significant amount of the apoptotic cell death that occurs as a result of inducing epilepsy. Mutations in the CTSB gene have been linked to tropical pancreatitis, a form of chronic pancreatitis. |
| Immunogen | recombinant protein |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG1 |
| Host Species | Mouse |
| Tested Applications | WBICCIHC |
| WB:1:5,000-1:10,000 ICC:1:200-1:500 |
|
| Species Reactivity | HumanZebra Fish |
| Concentration | 2mg/ml |
| Alternative Names | Amyloid precursor protein secretase antibody APP secretase antibody APPS antibody CATB_HUMAN antibody Cathepsin B heavy chain antibody Cathepsin B1 antibody CathepsinB antibody CPSB antibody CTSB antibody cysteine protease antibody OTTHUMP00000116009 antibody OTTHUMP00000229510 antibody OTTHUMP00000229511 antibody OTTHUMP00000229512 antibody OTTHUMP00000229514 antibody OTTHUMP00000229515 antibody OTTHUMP00000229516 antibody Preprocathepsin B antibody |
|---|---|
| Molecular Weight(MW) | 38kDa |
| Cellular Localization | Lysosome, secreted |
| SwissProt ID | P07858 |
|---|
Application
Fig1: Western blot analysis of Cathepsin B on SW480 cell lysate using anti-Cathepsin B antibody at 1/5,000 dilution.
Application
Fig2: ICC staining Cathepsin B (red) in HepG2 cells. Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
Application
Fig3: Western blot analysis of Cathepsin B on hybrid fish (crucian-carp) brain tissue lysate using anti-Cathepsin B antibody at 1/500 dilution.| Positive Control | SW480, HepG2 |
|---|---|
| Application Notes | WB:1:5,000-1:10,000 ICC:1:200-1:500 |
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles. |
| Storage Buffer | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
