Application
Fig1: Immunohistochemical analysis of paraffin-embedded human tonsil tissue using anti-CD34 mouse mAb.Application
Fig2: Immunohistochemical analysis of paraffin-embedded human kidney tissue using anti- CD34 mouse mAb.Application
Fig3: Immunohistochemical analysis of paraffin-embedded mouse lung tissue using anti- CD34 mouse mAb.| Product Name | CD34 [2-E9] |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | CD34 antibody CD34 antigen antibody CD34 molecule antibody CD34_HUMAN antibody Cluster designation 34 antibody Hematopoietic progenitor cell antigen CD34 antibody HPCA1 antibody Mucosialin antibody OTTHUMP00000034733 antibody OTTHUMP00000034734 antibody |
| Product description | CD34 is a heavily glycosylated type I transmembrane molecule, that can be phoshorylated by a variety of kinases including Protein kinase C and Tyrosine kinases. CD34 antigen is expressed on small vessel endothelial cells and tumors of epithelial origin. CD34 is possibly an adhesion molecule with a putative role in early hematopoiesis by mediating the attachment of stem cells to the bone marrow extracellular matrix or directly to stromal cells. It could act as a scaffold for the attachment of lineage specific glycans, allowing stem cells to bind to lectins expressed by stromal cells or other marrow components. So CD34 is considered to be ideal marker for identifying and quantifying hematopoietic progenitor stem cells. With interaction with CrkL, CD34 becomes a substrate for PKC and CD34 surface expression is associated with activation of PKC. |
| Immunogen | recombinant protein |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG1 |
| Host Species | Mouse |
| Tested Applications | WBICCIHC |
| IHC:1:200-1:500 WB |
|
| Species Reactivity | HumanMouse |
| Concentration | 2mg/ml |
| Alternative Names | CD34 antibody CD34 antigen antibody CD34 molecule antibody CD34_HUMAN antibody Cluster designation 34 antibody Hematopoietic progenitor cell antigen CD34 antibody HPCA1 antibody Mucosialin antibody OTTHUMP00000034733 antibody OTTHUMP00000034734 antibody |
|---|---|
| Molecular Weight(MW) | 100kDa |
| Cellular Localization | Cell membrane |
| SwissProt ID | P28906 |
|---|
Application
Fig1: Immunohistochemical analysis of paraffin-embedded human tonsil tissue using anti-CD34 mouse mAb.
Application
Fig2: Immunohistochemical analysis of paraffin-embedded human kidney tissue using anti- CD34 mouse mAb.
Application
Fig3: Immunohistochemical analysis of paraffin-embedded mouse lung tissue using anti- CD34 mouse mAb.| Positive Control | Human tonsil, human kidney, mouse lung |
|---|---|
| Application Notes | IHC:1:200-1:500 WB |
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles. |
| Storage Buffer | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
