Application
Fig1: Western blot analysis of ABC1 expression in MES-SA/Dx5 whole cell lysate.| Product Name | ABCA1 [4G2] |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | ABC 1 antibody ABC Transporter 1 antibody ABC-1 antibody ABC1 antibody ABCA 1 antibody ABCA1 antibody ABCA1_HUMAN antibody ATP binding Cassette 1 antibody ATP binding cassette sub family A ABC1 member 1 antibody ATP binding cassette sub family A member 1 antibody ATP binding Cassette Transporter 1 antibody ATP-binding cassette 1 antibody ATP-binding cassette sub-family A member 1 antibody ATP-binding cassette transporter 1 antibody CERP antibody Cholesterol efflux regulatory protein antibody FLJ14958 antibody HDLDT1 antibody Membrane bound antibody MGC164864 antibody MGC165011 antibody TD antibody TGD antibody |
| Product description | ABC1 (for ATP-binding cassette transporter 1) is a member of the family of ATP-binding cassette proteins which transport various molecules across biological membranes. ABC1 contains 2 characteristic ATP-binding domains and 12 transmembrane domains which form a channel-like structure for transport. Mutations in the ABC1 gene are implicated in Tangier disease, characterized by low serum high density lipoprotein. ABC1 is widely expressed in human tissues, with high levels of expression in liver, lung, adrenal glands, placenta and fetal tissue. ABC1 expression is induced during monocyte differentiation and upregulated in the presence of acetylated low-density lipoprotein. ABC1 may have a dual regulatory function in macrophage lipid metabolism and inflammation. |
| Immunogen | peptide |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG1 |
| Host Species | Mouse |
| Tested Applications | WBIPIFIHC-P |
| WB:1:100-1:1,000 IP:1-2 μg per 100-500 μg of total protein(1 ml of cell lysate) IF:1:50-500 IHC:1:50-500 |
|
| Species Reactivity | HumanMouse |
| Concentration | 2mg/ml |
| Alternative Names | ABC 1 antibody ABC Transporter 1 antibody ABC-1 antibody ABC1 antibody ABCA 1 antibody ABCA1 antibody ABCA1_HUMAN antibody ATP binding Cassette 1 antibody ATP binding cassette sub family A ABC1 member 1 antibody ATP binding cassette sub family A member 1 antibody ATP binding Cassette Transporter 1 antibody ATP-binding cassette 1 antibody ATP-binding cassette sub-family A member 1 antibody ATP-binding cassette transporter 1 antibody CERP antibody Cholesterol efflux regulatory protein antibody FLJ14958 antibody HDLDT1 antibody Membrane bound antibody MGC164864 antibody MGC165011 antibody TD antibody TGD antibody |
|---|---|
| Molecular Weight(MW) | 220 kDa |
| Cellular Localization | Membrane |
| SwissProt ID | O95477 |
|---|
Application
Fig1: Western blot analysis of ABC1 expression in MES-SA/Dx5 whole cell lysate.| Positive Control | MES-SA/Dx5 |
|---|---|
| Application Notes | WB:1:100-1:1,000 IP:1-2 μg per 100-500 μg of total protein(1 ml of cell lysate) IF:1:50-500 IHC:1:50-500 |
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4℃ |
| Storage Buffer | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
