Application
Fig1: Western blot analysis of ATGL expression in SJRH30 (A) and Y79 (B) whole cell lysates.| Product Name | ATGL [4G5] |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | 1110001C14Rik antibody Adipose triglyceride lipase antibody ATGL antibody ATGL DESNUTRIN antibody Calcium independent phospholipase A2 antibody Calcium-independent phospholipase A2 antibody Desnutrin antibody EC 3.1.1.3 antibody FP17548 antibody IPLA2 zeta antibody IPLA2-zeta antibody PATATIN LIKE PHOSPHOLIPASE DOMAIN CONTAINING PROTEIN 2 antibody Patatin-like phospholipase domain-containing protein 2 antibody PEDF R antibody PHOSPHOLIPASE A2 CALCIUM INDEPENDENT ZETA antibody Pigment epithelium derived factor antibody Pigment epithelium-derived factor antibody plpl antibody plpl2 antibody PLPL2_HUMAN antibody Pnpla2 antibody Transport secretion protein 2 antibody Transport secretion protein 2.2 antibody Transport-secretion protein 2 antibody Triglyceride hydrolase antibody TTS 2.2 antibody TTS2 antibody TTS2.2 antibody ZETA antibody |
| Product description | The Adiponutrin family members, which have been implicated in obesity and diabetes, consist of Adiponutrin (ADPN), GS1, GS2, GS2-like, PNPLA1, and adipose triglyceride lipase (ATGL), also designated Desnutrin or Patatin-like phospholipase domain-containing protein 2 (PLNPA2). AGTL is a 486-amino acid protein that is highly expressed in mouse and human adipose tissue. It contains a highly conserved 180-amino acid N-terminal patatin domain common to plant acyl-hydrolases with a glycine-rich region, an aspartate active site motif, and an active serine hydrolase motif. Along with hormone-sensitive lipase, ATGL catabolizes stored triglycerides in mammalian adipose tissue. The lipase activity of AGTL is dependent upon the presence of an activated serine residue. ADPN and ATGL are oppositely regulated by insulin, where upregulation of ATGl and downregulation of ADPN occurs when fasting. |
| Immunogen | peptide |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG1 |
| Host Species | Mouse |
| Tested Applications | WBIPIF |
| WB:1:100-1:1,000 IP:1-2 μg per 100-500 μg of total protein(1 ml of cell lysate) IF:1:50-500 |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 2mg/ml |
| Alternative Names | 1110001C14Rik antibody Adipose triglyceride lipase antibody ATGL antibody ATGL DESNUTRIN antibody Calcium independent phospholipase A2 antibody Calcium-independent phospholipase A2 antibody Desnutrin antibody EC 3.1.1.3 antibody FP17548 antibody IPLA2 zeta antibody IPLA2-zeta antibody PATATIN LIKE PHOSPHOLIPASE DOMAIN CONTAINING PROTEIN 2 antibody Patatin-like phospholipase domain-containing protein 2 antibody PEDF R antibody PHOSPHOLIPASE A2 CALCIUM INDEPENDENT ZETA antibody Pigment epithelium derived factor antibody Pigment epithelium-derived factor antibody plpl antibody plpl2 antibody PLPL2_HUMAN antibody Pnpla2 antibody Transport secretion protein 2 antibody Transport secretion protein 2.2 antibody Transport-secretion protein 2 antibody Triglyceride hydrolase antibody TTS 2.2 antibody TTS2 antibody TTS2.2 antibody ZETA antibody |
|---|---|
| Molecular Weight(MW) | 55 kDa |
| Cellular Localization | Cell membrane, Lipid droplet |
| SwissProt ID | Q96AD5 |
|---|
Application
Fig1: Western blot analysis of ATGL expression in SJRH30 (A) and Y79 (B) whole cell lysates.| Positive Control | SJRH30, Y79. |
|---|---|
| Application Notes | WB:1:100-1:1,000 IP:1-2 μg per 100-500 μg of total protein(1 ml of cell lysate) IF:1:50-500 |
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4℃ |
| Storage Buffer | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
