| Product Name | Human IgG4 [2G1] |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | Ig gamma 4 chain C region antibody IGHG4 antibody immunoglobulin heavy chain constant region gamma 4 antibody Immunoglobulin heavy constant gamma 4 (G4m marker) antibody MGC117419 antibody |
| Product description | The regions of relatively constant sequence beyond the variable regions of immunoglobulins are termed constant regions (C regions) and are present in both the heavy and light chains. With very few exceptions, the sites of attachment for carbohydrates on immunoglobulins are located in these C regions. These regions also function to hold the variable regions together by using the disulfide bond between them. The C regions facilitate interaction with the antigen by increasing the maximum rotation of the immunoglobulin arms. Several studies have shown that a large population of patients with recurrent respiratory tract infection have low IgG4 concentrations. |
| Immunogen | IgG4 of human origin. |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG1 |
| Host Species | Mouse |
| Tested Applications | ICC/IF |
| ELISA:1:30-1:3,000 |
|
| Species Reactivity | Human |
| Concentration | 2mg/ml |
| Alternative Names | Ig gamma 4 chain C region antibody IGHG4 antibody immunoglobulin heavy chain constant region gamma 4 antibody Immunoglobulin heavy constant gamma 4 (G4m marker) antibody MGC117419 antibody |
|---|---|
| Cellular Localization | Secreted |
| SwissProt ID | P01861 |
|---|
| Application Notes | ELISA:1:30-1:3,000 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4℃ |
| Storage Buffer | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
