Application
Fig1: Western blot analysis of human recombinant SAA.Application
Fig2： Western blot analysis of SAA expression in Caki-1 whole cell lysate (A) and of SAA human plasma (B).| Product Name | Serum Amyloid A (SAA) [4G08] |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | Amyloid fibril protein AA antibody Amyloid fibrils antibody Amyloid protein A antibody Fibrils antibody MGC111216 antibody OC antibody PIG 4 antibody PIG4 antibody SAA 1 antibody SAA 2 antibody SAA antibody SAA_HUMAN antibody SAA1 antibody SAA2 antibody Serum amyloid A protein precursor antibody Serum amyloid A1 isoform 1 antibody Serum amyloid A1 isoform 2 antibody Serum amyloid protein A(4-101) antibody TP53I4 antibody Tumor protein p53 inducible protein 4 antibody |
| Product description | The serum Amyloid A (SAA) family of proteins is encoded by muliple genes, which display allelic variation and a high degree of homology in mammals. The four members of the SAA gene family are clustered on human chromo- some 11p15.1. Three SAA genes are differentially expressed and encode small apolipoproteins. SAA1 and SAA2 encode the acute phase SAAs (A-SAAs) and SAA4 encodes the constitutively expressed SAA (C-SAA). A fourth locus, SAA3, is a pseudogene that contains two C/EBP-binding sites and a third site, which interacts with SAA3 enhancer factor . Human SAA proteins are a group of apolipoproteins found predominantly in the high-density lipoprotein (HDL) fraction of plasma. SAA is a major acute-phase protein and precursor to Amyloid A protein, which is the major constituent of the fibril deposits of reactive amyloidosis. SAA is secreted in large amounts by the liver during microbial infections or inflammatory diseases. |
| Immunogen | Highly purified recombinant SAA of human origin |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG1 |
| Host Species | Mouse |
| Tested Applications | WBIP |
| WB:1:100-1:1,000 IP:1-2 μg per 100-500 μg of total protein(1 ml of cell lysate) |
|
| Species Reactivity | Human |
| Concentration | 2mg/ml |
| Alternative Names | Amyloid fibril protein AA antibody Amyloid fibrils antibody Amyloid protein A antibody Fibrils antibody MGC111216 antibody OC antibody PIG 4 antibody PIG4 antibody SAA 1 antibody SAA 2 antibody SAA antibody SAA_HUMAN antibody SAA1 antibody SAA2 antibody Serum amyloid A protein precursor antibody Serum amyloid A1 isoform 1 antibody Serum amyloid A1 isoform 2 antibody Serum amyloid protein A(4-101) antibody TP53I4 antibody Tumor protein p53 inducible protein 4 antibody |
|---|---|
| Molecular Weight(MW) | 12kDa |
| Cellular Localization | Secreted |
| SwissProt ID | P02735 |
|---|
Application
Fig1: Western blot analysis of human recombinant SAA.
Application
Fig2： Western blot analysis of SAA expression in Caki-1 whole cell lysate (A) and of SAA human plasma (B).| Positive Control | Caki-1, human recombinant SAA |
|---|---|
| Application Notes | WB:1:100-1:1,000 IP:1-2 μg per 100-500 μg of total protein(1 ml of cell lysate) |
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4℃ |
| Storage Buffer | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
