Purified recombinant fragment of human CD206 (AA: extra(19-218)) expressed in E. Coli.
Key Feature
Clonality
Monoclonal
Isotype
IgG2a
Host Species
Mouse
Tested Applications
FCMIHC
IHC:1:200-1:1000 FCM:1:200-1:400
Species Reactivity
Human
Concentration
1mg/ml
Purification
Affinity purified
Target Information
Gene Symbol
MRC1
Gene Synonyms
MMR hMR CD206 MRC1L1 CLEC13D CLEC13DL bA541I19.1
Gene Full Name
mannose receptor C-type 1
Gene Summary
The recognition of complex carbohydrate structures on glycoproteins is an important part of several biological processes, including cell-cell recognition, serum glycoprotein turnover, and neutralization of pathogens. The protein encoded by this gene is a type I membrane receptor that mediates the endocytosis of glycoproteins by macrophages. The protein has been shown to bind high-mannose structures on the surface of potentially pathogenic viruses, bacteria, and fungi so that they can be neutralized by phagocytic engulfment.[provided by RefSeq, Sep 2015]
Alternative Names
MMR hMR CD206 MRC1L1 CLEC13D CLEC13DL bA541I19.1
Cellular Localization
Cell membrane, Endosome, Membrane
Application
IHC
Immunohistochemical analysis of paraffin-embedded human cervical cancer tissues using CD206 mouse mAb with DAB staining.
FCM
Flow cytometric analysis of MOLT4 cells using CD206 mouse mAb (green) and negative control (red).
Application Notes
IHC:1:200-1:1000 FCM:1:200-1:400
Additional Information
Form
Liquid
Storage Instructions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.