Recombinant human projection domain
sequence, amino acids 377-1505
Key Feature
Clonality
polyclonal
Isotype
IgY
Host Species
Chicken
Tested Applications
ICC/IF
ICC/IF:1:5000-1:10000
Species Reactivity
HumanMouseRat
Concentration
1mg/ml
Purification
Affinity purified
Target Information
Gene Symbol
MAP2
Gene Synonyms
MAP-2 MAP2A MAP2B MAP2C
Gene Full Name
microtubule associated protein 2
Gene Summary
This gene encodes a protein that belongs to the microtubule-associated protein family. The proteins of this family are thought to be involved in microtubule assembly, which is an essential step in neurogenesis. The products of similar genes in rat and mouse are neuron-specific cytoskeletal proteins that are enriched in dentrites, implicating a role in determining and stabilizing dentritic shape during neuron development. A number of alternatively spliced variants encoding distinct isoforms have been described. [provided by RefSeq, Jan 2010]
Cellular Localization
Cytoplasm, cytoskeleton
Application
ICC/IF
Image of primary neuronal culture showing neuronal staining with MAP2 (green) and astrocytes with GFAP (red). Nuclei are counterstained blue.
Application Notes
ICC/IF:1:5000-1:10000
Additional Information
Form
Liquid
Storage Instructions
Antibody can also be aliquotted and stored frozen at -20° C to -70° C in a
manual defrost freezer for six months without detectable loss of activity. The
antibody can be stored at 2° -8° C for 1 month without detectable loss of
activity. Avoid repeated freeze-thaw cycles.