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Rabbit anti-TSLP Polyclonal antibody

Catalog Number:OM644464
OM644464
Discount Price
OM644464-100ul
100ul
OM644464-50ul
50ul
Product Profile
Product Name Rabbit anti-TSLP Polyclonal antibody
Antibody Type Primary Antibodies
Immunogen Recombinant Human Thymic stromal lymphopoietin protein (29-159AA).
Key Feature
Clonality Polyclonal
Isotype IgG
Host Species Rabbit
Tested Applications IHCWB
WB:1:500-1:5000
IHC:1:20-1:200
Species Reactivity HumanMouse
Concentration 1mg/ml
Purification Protein G
Target Information
Gene Symbol TSLP
Gene Full Name thymic stromal lymphopoietin
Gene Summary This gene encodes a hemopoietic cytokine proposed to signal through a heterodimeric receptor complex composed of the thymic stromal lymphopoietin receptor and the IL-7R alpha chain. It mainly impacts myeloid cells and induces the release of T cell-attracting chemokines from monocytes and enhances the maturation of CD11c(+) dendritic cells. The protein promotes T helper type 2 (TH2) cell responses that are associated with immunity in various inflammatory diseases, including asthma, allergic inflammation and chronic obstructive pulmonary disease. The protein is therefore considered a potential therapeutic target for the treatment of such diseases. In addition, the shorter (predominant) isoform is an antimicrobial protein, displaying antibacterial and antifungal activity against B. cereus, E. coli, E. faecalis, S. mitis, S. epidermidis, and C. albicans. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Jul 2020]
Alternative Names Thymic stromal lymphopoietin antibody
Thymic stromal lymphopoietin protein TSLP antibody
Tslp antibody
TSLP protein antibody
TSLP_HUMAN antibody
Molecular Weight(MW) 19kDa
Cellular Localization Secreted
Application

WB

Positive WB detected in: U87 whole cell lysate, SH-SY5Y whole cell lysate, Mouse liver tissue, All lanes: TSLP antibody at 3.4µg/ml, Secondary Goat polyclonal to rabbit IgG at 1/50000 dilution.

IHC

Immunohistochemistry of paraffin-embedded human prostate tissue using TSLP Antibody at dilution of 1:100.
Application Notes WB:1:500-1:5000
IHC:1:20-1:200
Additional Information
Form Liquid
Storage Instructions Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Storage Buffer Preservative: 0.03% Proclin 300,Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
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