IHC
Formalin-fixed, paraffin-embedded human Hepatocellular Carcinoma stained with HepPar-1 Monoclonal Antibody (HepPar1).| Product Name | HepPar-1 (Hepatocellular Marker) Antibody - With BSA and Azide |
|---|---|
| Antibody Type | Primary Antibodies |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG1 |
| Host Species | Mouse |
| Tested Applications | ICC/IFIHC |
| IHC:1:50-1:200 ICC/IF:1:50-1:200 |
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| Species Reactivity | DogHuman |
| Purification | Affinity purified |
| Function | Hepatocyte Paraffin 1 or HepPar1 localizes to the mitochondria of hepatocytes. It is a sensitive marker for distinguishing hepatocellular carcinomas (HCC) from other metastatic carcinomas as well as cholangio-carcinomas. HCC s occur primarily in the stomach, but they are also found in many other organs. The Hepatocyte Specific Antigen may also be a useful marker for intestinal metaplasia. Reportedly, strong expression of the Hepatocyte Specific Antigen correlates with smaller tumor size and longer patient survival. Occasionally, Hepatocyte Specific Antigen is also found in gastric carcinomas as well as in a few other non-hepatic tumors. |
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IHC
Formalin-fixed, paraffin-embedded human Hepatocellular Carcinoma stained with HepPar-1 Monoclonal Antibody (HepPar1).| Application Notes | IHC:1:50-1:200 ICC/IF:1:50-1:200 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing. |
| Storage Buffer | Clear, colorless solution in phosphate buffered saline, pH 7.2 . |
