WB
Western blot analysis of RAPGEF6 expression in HeLa nuclear extracts.IHC
Immunoperoxidase staining of human pancreatic tissue fixed in formalin and embedded in paraffin reveals membrane and cytoplasmic localization.ICC/IF
Immunofluorescence staining of HeLa cells fixed with paraformaldehyde reveals the localization of the nucleus and cytoplasm.| Product Name | Mouse Monoclonal antibody to RAPGEF6 |
|---|---|
| Antibody Type | Primary Antibodies |
| Immunogen | raised against recombinant RAPGEF6 of human origin. |
| Clonality | monoclonal |
|---|---|
| Isotype | IgG2a,k |
| Host Species | Mouse |
| Tested Applications | ICC/IFIHCWB |
| WB:1:100-1:1000 IHC:1:50-1:500 ICC/IF:1:50-1:500 |
|
| Species Reactivity | Human |
| Concentration | 0.1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | RAPGEF6 |
|---|---|
| Gene Synonyms | RAGEF2 PDZGEF2 KIA001LB PDZ-GEF2 RA-GEF-2 |
| Gene Full Name | Rap guanine nucleotide exchange factor 6 |
| Gene Summary | Enables several functions, including GTP-dependent protein binding activity; guanyl-nucleotide exchange factor activity; and phosphatidic acid binding activity. Involved in microvillus assembly; positive regulation of GTPase activity; and protein localization to plasma membrane. Located in several cellular components, including apical plasma membrane; centrosome; and endocytic vesicle. [provided by Alliance of Genome Resources, Jul 2025] |
| Molecular Weight(MW) | 179kDa |
WB
Western blot analysis of RAPGEF6 expression in HeLa nuclear extracts.
IHC
Immunoperoxidase staining of human pancreatic tissue fixed in formalin and embedded in paraffin reveals membrane and cytoplasmic localization.
ICC/IF
Immunofluorescence staining of HeLa cells fixed with paraformaldehyde reveals the localization of the nucleus and cytoplasm.| Application Notes | WB:1:100-1:1000 IHC:1:50-1:500 ICC/IF:1:50-1:500 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Store at 4° C, **DO NOT FREEZE**. Stable for one year from the date of shipment. Non-hazardous. No MSDS required. |
| Storage Buffer | Each vial contains 100 µg IgG2a kappa light chain in 1.0 ml of PBS with < 0.1% sodium azide and 0.1% gelatin. |
