WB
Near infrared western blot analysis of plakophilin 1 expression in A-431 (A), ME-180 (B), and A-673 (C) whole cell lysate.WB
Western blot analysis of plakophilin 1 expression in A-431 (A) and RAW 264.7 (B) whole cell lysate.| Product Name | Mouse Monoclonal antibody to plakophilin 1 |
|---|---|
| Antibody Type | Primary Antibodies |
| Immunogen | raised against the N-terminus of plakophilin 1 of human origin, eptiope mapping to amino acids 1-27 of human plakophilin 1. |
| Clonality | monoclonal |
|---|---|
| Isotype | IgG1, k |
| Host Species | Mouse |
| Tested Applications | WB |
| WB:1:100-1:1000 |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 0.2mg/ml |
| Purification | Affinity purified |
| Gene Symbol | PKP1 |
|---|---|
| Gene Synonyms | B6P EDSFS |
| Gene Full Name | plakophilin 1 |
| Gene Summary | This gene encodes a member of the arm-repeat (armadillo) and plakophilin gene families. Plakophilin proteins contain numerous armadillo repeats, localize to cell desmosomes and nuclei, and participate in linking cadherins to intermediate filaments in the cytoskeleton. This protein may be involved in molecular recruitment and stabilization during desmosome formation. Mutations in this gene have been associated with the ectodermal dysplasia/skin fragility syndrome. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2010] |
| Molecular Weight(MW) | 75 kDa |
WB
Near infrared western blot analysis of plakophilin 1 expression in A-431 (A), ME-180 (B), and A-673 (C) whole cell lysate.
WB
Western blot analysis of plakophilin 1 expression in A-431 (A) and RAW 264.7 (B) whole cell lysate.| Application Notes | WB:1:100-1:1000 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Store at 4° C, **DO NOT FREEZE**. Stable for one year from the date of shipment. Non-hazardous. No MSDS required. |
| Storage Buffer | Each vial contains 200 µg IgG1 kappa light chain in 1.0 ml of PBS with < 0.1% sodium azide and 0.1% gelatin. |
