WB
Western blot analysis of HAP1 expression in mouse cerebellum (A) and mouse brain (B) tissue extracts.WB
Western blot analysis of HAP1 expression in Neuro-2A whole cell lysate.| Product Name | Mouse Monoclonal antibody to HAP1 |
|---|---|
| Antibody Type | Primary Antibodies |
| Immunogen | raised against cDNA residues 290-426 of HAP1 of rat origin. |
| Clonality | monoclonal |
|---|---|
| Isotype | IgG1, k |
| Host Species | Mouse |
| Tested Applications | WB |
| WB:1:100-1:1000 |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 0.2mg/ml |
| Purification | Affinity purified |
| Gene Symbol | HAP1 |
|---|---|
| Gene Synonyms | HLP HAP2 HIP5 hHLP1 |
| Gene Full Name | huntingtin associated protein 1 |
| Gene Summary | Huntington's disease (HD), a neurodegenerative disorder characterized by loss of striatal neurons, is caused by an expansion of a polyglutamine tract in the HD protein huntingtin. This gene encodes a protein that interacts with huntingtin, with two cytoskeletal proteins (dynactin and pericentriolar autoantigen protein 1), and with a hepatocyte growth factor-regulated tyrosine kinase substrate. The interactions with cytoskeletal proteins and a kinase substrate suggest a role for this protein in vesicular trafficking or organelle transport. Several alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jul 2008] |
| Molecular Weight(MW) | 75-85 kDa |
| Cellular Localization | Cell projection,Cytoplasm,Cytoplasmic vesicle,Cytoskeleton,Endoplasmic reticulum. |
WB
Western blot analysis of HAP1 expression in mouse cerebellum (A) and mouse brain (B) tissue extracts.
WB
Western blot analysis of HAP1 expression in Neuro-2A whole cell lysate.| Application Notes | WB:1:100-1:1000 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Store at 4° C, **DO NOT FREEZE**. Stable for one year from the date of shipment. Non-hazardous. No MSDS required. |
| Storage Buffer | Each vial contains 200 µg IgG1 kappa light chain in 1.0 ml of PBS with < 0.1% sodium azide and 0.1% gelatin. |
