WB
All lanes: DHCR24 antibody at 2μg/ml + Jurkat whole cell lysate, Secondary Goat polyclonal to rabbit IgG at 1/10000 dilution.IHC
Immunohistochemistry of paraffin-embedded human breast cancer using DHCR24 Antibody at dilution of 1:100.IHC
Immunohistochemistry of paraffin-embedded human placenta tissue using DHCR24 Antibody at dilution of 1:100.| Product Name | Rabbit anti-DHCR24 Polyclonal antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Immunogen | Recombinant Human Delta(24)-sterol reductase protein (227-516AA) |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | IHCWB |
| WB:1:200-1:1000 IHC:1:20-1:200 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | DHCR24 |
|---|---|
| Gene Synonyms | DCE SELADIN1 Nbla03646 seladin-1 |
| Gene Full Name | 24-dehydrocholesterol reductase |
| Gene Summary | This gene encodes a flavin adenine dinucleotide (FAD)-dependent oxidoreductase which catalyzes the reduction of the delta-24 double bond of sterol intermediates during cholesterol biosynthesis. The protein contains a leader sequence that directs it to the endoplasmic reticulum membrane. Missense mutations in this gene have been associated with desmosterolosis. Also, reduced expression of the gene occurs in the temporal cortex of Alzheimer disease patients and overexpression has been observed in adrenal gland cancer cells. [provided by RefSeq, Jul 2008] |
| Alternative Names | 24 dehydrocholesterol reductase antibody 24-dehydrocholesterol reductase antibody 3 beta hydroxysterol delta 24 reductase antibody 3-beta-hydroxysterol delta-24-reductase antibody DCE antibody Delta(24)-sterol reductase antibody Desmosterol to cholesterol enzyme antibody DHC24_HUMAN antibody Dhcr24 antibody Diminuto dwarf1 homolog antibody Diminuto/dwarf1 homolog antibody KIAA0018 antibody Nbla03646 antibody Seladin-1 antibody SELADIN1 antibody Selective AD indicator 1 antibody Selective Alzheimer's Disease Indicator 1 antibody |
| Molecular Weight(MW) | 61 kDa |
| Cellular Localization | Endoplasmic reticulum membrane; Single-pass membrane protein. Golgi apparatus membrane; Single-pass membrane protein. |
WB
All lanes: DHCR24 antibody at 2μg/ml + Jurkat whole cell lysate, Secondary Goat polyclonal to rabbit IgG at 1/10000 dilution.
IHC
Immunohistochemistry of paraffin-embedded human breast cancer using DHCR24 Antibody at dilution of 1:100.
IHC
Immunohistochemistry of paraffin-embedded human placenta tissue using DHCR24 Antibody at dilution of 1:100.| Application Notes | WB:1:200-1:1000 IHC:1:20-1:200 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
| Storage Buffer | 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
