WB
Positive WB detected in: A549 whole cell lysate, HL60 whole cell lysate, Hela whole cell lysate, SH-SY5Y whole cell lysate, Rat spleen tissue. All lanes: BACE2 antibody at 2.5μg/ml, Secondary Goat polyclonal to rabbit IgG at 1/50000 dilution.IHC
Immunohistochemistry of paraffin-embedded human gastric cancer using BACE2 Antibody at dilution of 1:100.ICC/IF
Immunofluorescent analysis of A549 cells using BACE2 Antibody at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).| Product Name | Rabbit anti-BACE2 Polyclonal antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Immunogen | Recombinant Human Beta-secretase 2 protein (84-157AA) |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | ICC/IFIHCWB |
| WB:1:500-1:5000 IHC:1:20-1:200 ICC/IF:1:50-1:200 |
|
| Species Reactivity | HumanRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | BACE2 |
|---|---|
| Gene Synonyms | ASP1 BAE2 DRAP AEPLC ALP56 ASP21 CDA13 CEAP1 |
| Gene Full Name | beta-secretase 2 |
| Gene Summary | This gene encodes an integral membrane glycoprotein that functions as an aspartic protease. The encoded protein cleaves amyloid precursor protein into amyloid beta peptide, which is a critical step in the etiology of Alzheimer's disease and Down syndrome. The protein precursor is further processed into an active mature peptide. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013] |
| Alternative Names | ALP 56 antibody ALP56 antibody Asp 1 antibody ASP1 antibody ASP21 antibody Aspartic Like Protease 56kDa antibody Aspartic-like protease 56 kDa antibody Aspartyl protease 1 antibody BACE 2 antibody Bace2 antibody BACE2_HUMAN antibody Beta Secretase 2 antibody Beta Site Amyloid Beta A4 Precursor Protein Cleaving Enzyme 2 antibody Beta-secretase 2 antibody Beta-site amyloid precursor protein cleaving enzyme 2 antibody Beta-site APP cleaving enzyme 2 antibody Down region aspartic protease antibody Downs Syndrome Region Aspartic Protease antibody DRAP antibody Memapsin 1 antibody Memapsin-1 antibody Membrane associated aspartic protease 1 antibody Membrane-associated aspartic protease 1 antibody Theta-secretase antibody |
| Molecular Weight(MW) | 57 kDa,43 kDa |
| Cellular Localization | Cell membrane; Single-pass type I membrane protein. Golgi apparatus. Endoplasmic reticulum. Endosome. |
WB
Positive WB detected in: A549 whole cell lysate, HL60 whole cell lysate, Hela whole cell lysate, SH-SY5Y whole cell lysate, Rat spleen tissue. All lanes: BACE2 antibody at 2.5μg/ml, Secondary Goat polyclonal to rabbit IgG at 1/50000 dilution.
IHC
Immunohistochemistry of paraffin-embedded human gastric cancer using BACE2 Antibody at dilution of 1:100.
ICC/IF
Immunofluorescent analysis of A549 cells using BACE2 Antibody at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).| Application Notes | WB:1:500-1:5000 IHC:1:20-1:200 ICC/IF:1:50-1:200 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
| Storage Buffer | 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
