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Monoclonal Antibody to Atrophin 1 (ATN1)

Catalog Number:OM645628
OM645628
Discount Price
OM645628-100ul
100ul
Product Profile
Product Name Monoclonal Antibody to Atrophin 1 (ATN1)
Antibody Type Primary Antibodies
Immunogen Recombinant ATN1 (Asp879~Leu1190) expressed in E.coli
Key Feature
Clonality Monoclonal
Isotype IgG2b,k
Host Species Mouse
Tested Applications IHCWB
WB:0.01-2µg/mL
IHC:5-20µg/mL
Species Reactivity Human
Concentration 1mg/ml
Purification Protein A/G
Target Information
Gene Symbol ATN1
Gene Synonyms B37
HRS
NOD
DRPLA
CHEDDA
D12S755E
Gene Full Name atrophin 1
Gene Summary Dentatorubral pallidoluysian atrophy (DRPLA) is a rare neurodegenerative disorder characterized by cerebellar ataxia, myoclonic epilepsy, choreoathetosis, and dementia. The disorder is related to the expansion from 7-35 copies to 49-93 copies of a trinucleotide repeat (CAG/CAA) within this gene. The encoded protein includes a serine repeat and a region of alternating acidic and basic amino acids, as well as the variable glutamine repeat. Alternative splicing results in two transcripts variants that encode the same protein. [provided by RefSeq, Jul 2016]
Alternative Names B37
DRPLA
NOD
Dentatorubral Pallidoluysian Atrophy
Application

WB

Western Blot; Sample: U87MG cell lysate Primary Ab: 0.5µg/ml Mouse Anti-Human ATN1 Antibody Second Ab: 0.2µg/ml HRP-Linked Caprine Anti-Mouse IgG Polyclonal Antibody.

IHC

DAB staining on IHC-P;Samples:Human Glioma Tissue.
Application Notes WB:0.01-2µg/mL
IHC:5-20µg/mL
Additional Information
Form Liquid
Storage Instructions Avoid repeated freeze/thaw cycles. Store at 4ºC for frequent use. Aliquot and store at -20ºC for 24 months.
Storage Buffer Supplied as solution form in 0.01M PBS, pH7.4, containing 0.05% Proclin-300,50% glycerol.
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