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Monoclonal Antibody to Lipopolysaccharide Binding Protein (LBP)

Catalog Number:OM645746
OM645746
Discount Price
OM645746-100ul
100ul
Product Profile
Product Name Monoclonal Antibody to Lipopolysaccharide Binding Protein (LBP)
Antibody Type Primary Antibodies
Immunogen Recombinant LBP (Asn27~Val481) expressed in E.coli
Key Feature
Clonality Monoclonal
Isotype IgG1, k
Host Species Mouse
Tested Applications IHCWB
IHC:5-20µg/mL
WB:1:200-1:2000
Species Reactivity Human
Concentration 1mg/ml
Purification Protein A/G
Target Information
Gene Symbol LBP
Gene Synonyms BPIFD2
Gene Full Name lipopolysaccharide binding protein
Gene Summary The protein encoded by this gene is involved in the acute-phase immunologic response to gram-negative bacterial infections. Gram-negative bacteria contain a glycolipid, lipopolysaccharide (LPS), on their outer cell wall. Together with bactericidal permeability-increasing protein (BPI), the encoded protein binds LPS and interacts with the CD14 receptor, probably playing a role in regulating LPS-dependent monocyte responses. Studies in mice suggest that the encoded protein is necessary for the rapid acute-phase response to LPS but not for the clearance of LPS from circulation. This protein is part of a family of structurally and functionally related proteins, including BPI, plasma cholesteryl ester transfer protein (CETP), and phospholipid transfer protein (PLTP). [provided by RefSeq, Apr 2012]
Alternative Names LPS-Binding Protein
Molecular Weight(MW) 52 kDa
Application

WB

Figure. Western Blot; Sample: Recombinant LBP, Human.

IHC

DAB staining on IHC-P; Sample: Human Kidney Tissue; Primary Ab: 10µg/ml Mouse Anti-Human LBP Antibody Second Ab: 2µg/mL HRP-Linked Caprine Anti-Mouse IgG Polyclonal Antibody.
Application Notes IHC:5-20µg/mL
WB:1:200-1:2000
Additional Information
Form Liquid
Storage Instructions Avoid repeated freeze/thaw cycles. Store at 4ºC for frequent use. Aliquot and store at -20ºC for 24 months.
Storage Buffer Supplied as solution form in 0.01M PBS, pH7.4, containing 0.05% Proclin-300,50% glycerol.
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