Recombinant IL11 (Pro22~Leu199) expressed in E.coli
Key Feature
Clonality
Monoclonal
Isotype
IgG1, k
Host Species
Mouse
Tested Applications
WB
WB:0.01-2µg/mL
Species Reactivity
Human
Concentration
1mg/ml
Purification
Protein A/G
Target Information
Gene Symbol
IL11
Gene Synonyms
AGIF IL-11
Gene Full Name
interleukin 11
Gene Summary
The protein encoded by this gene is a member of the gp130 family of cytokines. These cytokines drive the assembly of multisubunit receptor complexes, all of which contain at least one molecule of the transmembrane signaling receptor IL6ST (gp130). This cytokine is shown to stimulate the T-cell-dependent development of immunoglobulin-producing B cells. It is also found to support the proliferation of hematopoietic stem cells and megakaryocyte progenitor cells. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jun 2012]