WB
Western blot analysis of SERCA2 expression in HeLa cell lysate.| Product Name | Rabbit monoclonal antibody to SERCA2/ATP2A2 |
|---|---|
| Antibody Type | Primary Antibodies |
| Immunogen | A synthesized peptide derived from human Poliovirus Receptor. |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:500-1:2000 |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 0.5mg/ml |
| Purification | Affinity purified |
| Gene Symbol | ATP2A2 |
|---|---|
| Gene Synonyms | DD DAR ATP2B SERCA2 RHABDO2 |
| Gene Full Name | ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2 |
| Gene Summary | This gene encodes one of the SERCA Ca(2+)-ATPases, which are intracellular pumps located in the sarcoplasmic or endoplasmic reticula of the skeletal muscle. This enzyme catalyzes the hydrolysis of ATP coupled with the translocation of calcium from the cytosol into the sarcoplasmic reticulum lumen, and is involved in regulation of the contraction/relaxation cycle. Mutations in this gene cause Darier-White disease, also known as keratosis follicularis, an autosomal dominant skin disorder characterized by loss of adhesion between epidermal cells and abnormal keratinization. Other types of mutations in this gene have been associated with various forms of muscular dystrophies. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Dec 2019] |
| Alternative Names | ATP2A2 ATP2B Calcium pump 2 DAR DD DKFZp686P0211 FLJ20293 FLJ38063 SERCA2 SERCA2 ATP2A2 SERCA2b SR Ca(2+) ATPase 2 |
| Molecular Weight(MW) | 115 kDa |
| Cellular Localization | Endoplasmic reticulum,Membrane,Sarcoplasmic reticulum |
WB
Western blot analysis of SERCA2 expression in HeLa cell lysate.| Application Notes | WB:1:500-1:2000 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | 12 months from date of receipt, -20℃ as supplied. 6 months 2 to 8℃ after reconstitution. Avoid repeated freezing and thawing. |
| Storage Buffer | 500 ug/ml; Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide, 0.4-0.5 mg/ml BSA and 50% glycerol. |
