WB
Western blot analysis of VWF expression in human platelet extract (A) and HUV-EC-C whole cell lysate (B).IHC
Immunoperoxidase staining of formalin-fixed, embedded human tonsil tissue reveals cytoplasmic localization.IHC
Immunoperoxidase staining of formalin-fixed, paraffin-embedded human umbilical cord tissue shows membrane staining in umbilical vein endothelial cells.| Product Name | Mouse Monoclonal antibody to von Willebrand Factor/VWF |
|---|---|
| Antibody Type | Primary Antibodies |
| Immunogen | raised against VWF isolated from plasma of human origin. |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG1 |
| Host Species | Mouse |
| Tested Applications | IHCWB |
| WB:1:100-1:1000 IHC:1:50-1:500 |
|
| Species Reactivity | Human |
| Concentration | 0.1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | VWF |
|---|---|
| Gene Synonyms | VWD F8VWF |
| Gene Full Name | von Willebrand factor |
| Gene Summary | This gene encodes a glycoprotein involved in hemostasis. The encoded preproprotein is proteolytically processed following assembly into large multimeric complexes. These complexes function in the adhesion of platelets to sites of vascular injury and the transport of various proteins in the blood. Mutations in this gene result in von Willebrand disease, an inherited bleeding disorder. An unprocessed pseudogene has been found on chromosome 22. [provided by RefSeq, Oct 2015] |
| Molecular Weight(MW) | 250 kDa |
| Cellular Localization | Extracellular matrix,Secreted |
WB
Western blot analysis of VWF expression in human platelet extract (A) and HUV-EC-C whole cell lysate (B).
IHC
Immunoperoxidase staining of formalin-fixed, embedded human tonsil tissue reveals cytoplasmic localization.
IHC
Immunoperoxidase staining of formalin-fixed, paraffin-embedded human umbilical cord tissue shows membrane staining in umbilical vein endothelial cells.| Application Notes | WB:1:100-1:1000 IHC:1:50-1:500 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Store at 4° C, **DO NOT FREEZE**. Stable for one year from the date of shipment. Non-hazardous. No MSDS required. |
| Storage Buffer | Each vial contains 200 µg IgG1 kappa light chain in 1.0 ml of PBS with < 0.1% sodium azide and 0.1% gelatin. |
