WB
Neurofibromin Antibody: Western blot analysis of neurofibromin expression in NF1-knockout (A), rat (B), and human (C) Schwann cells. Kindly provided by Dr. David Muir, University of Florida College of Medicine.IHC
Neurofibromin Antibody:Immunoperoxidase staining of formalin-fixed, paraffin-embedded human liver tissue showing cytoplasmic staining in hepatic sinusoids.| Product Name | Mouse Monoclonal antibody to Neurofibromin |
|---|---|
| Antibody Type | Primary Antibodies |
| Immunogen | raised against amino acids 27-41 corresponding to an N-terminal peptide of Neurofibromin of human origin. |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG1, k |
| Host Species | Mouse |
| Tested Applications | IHCWB |
| WB:1:100-1:1000 IHC:1:50-1:500 |
|
| Species Reactivity | Human |
| Concentration | 0.1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | NF1 |
|---|---|
| Gene Synonyms | WSS NFNS VRNF |
| Gene Full Name | neurofibromin 1 |
| Gene Summary | This gene product appears to function as a negative regulator of the ras signal transduction pathway. Mutations in this gene have been linked to neurofibromatosis type 1, juvenile myelomonocytic leukemia and Watson syndrome. The mRNA for this gene is subject to RNA editing (CGA>UGA->Arg1306Term) resulting in premature translation termination. Alternatively spliced transcript variants encoding different isoforms have also been described for this gene. [provided by RefSeq, Jul 2008] |
| Molecular Weight(MW) | 250 kDa |
| Cellular Localization | Cell membrane,Membrane,Nucleus |
WB
Neurofibromin Antibody: Western blot analysis of neurofibromin expression in NF1-knockout (A), rat (B), and human (C) Schwann cells. Kindly provided by Dr. David Muir, University of Florida College of Medicine.
IHC
Neurofibromin Antibody:Immunoperoxidase staining of formalin-fixed, paraffin-embedded human liver tissue showing cytoplasmic staining in hepatic sinusoids.| Application Notes | WB:1:100-1:1000 IHC:1:50-1:500 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Store at 4° C, **DO NOT FREEZE**. Stable for one year from the date of shipment. Non-hazardous. No MSDS required. |
| Storage Buffer | Each vial contains 200 µg IgG1 kappa light chain in 1.0 ml of PBS with < 0.1% sodium azide and 0.1% gelatin. |
