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Mouse Monoclonal antibody to Islet-1

Catalog Number:OM646007
OM646007
Discount Price
OM646007-100ul
100ul
Product Profile
Product Name Mouse Monoclonal antibody to Islet-1
Antibody Type Primary Antibodies
Immunogen amino acids 244-282 of Islet-1 of human origin.
Key Feature
Clonality Monoclonal
Isotype IgG1, k
Host Species Mouse
Tested Applications WB
WB:1:100-1:1000
Species Reactivity HumanMouseRat
Concentration 0.1mg/ml
Purification Affinity purified
Target Information
Gene Symbol ISL1
Gene Synonyms Isl-1
ISLET1
Gene Full Name ISL LIM homeobox 1
Gene Summary This gene encodes a member of the LIM/homeodomain family of transcription factors. The encoded protein binds to the enhancer region of the insulin gene, among others, and may play an important role in regulating insulin gene expression. The encoded protein is central to the development of pancreatic cell lineages and may also be required for motor neuron generation. Mutations in this gene have been associated with maturity-onset diabetes of the young. [provided by RefSeq, Jul 2008]
Molecular Weight(MW) 39 kDa
Cellular Localization Nucleus
Application

WB

Islet-1 Antibody (B-1), HRP-conjugated. Western blot analysis of Islet-1 expression was performed using nuclear extract from HEL 92.1.7 cells (A), and whole-cell lysates from K-562 (B), MIA PaCa-2 (C), RAW 264.7 (D), HeLa (E), and PC-12 (F) cells

WB

Alexa Fluor® 790-conjugated Islet-1 Antibody (B-1):AF790. Direct near-infrared Western blot analysis of Islet-1 expression using nuclear extract from HEL 92.1.7 cells (A) and whole-cell lysates from K-562 (B) and MIA PaCa-2 (C) cells. Blots were blocked with UltraCruz® Blocking Reagent.
Application Notes WB:1:100-1:1000
Additional Information
Form Liquid
Storage Instructions Store at 4° C, **DO NOT FREEZE**. Stable for one year from the date of shipment. Non-hazardous. No MSDS required.
Storage Buffer Each vial contains 200 µg IgG1 kappa light chain in 1.0 ml of PBS with < 0.1% sodium azide and 0.1% gelatin.
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