WB
Western Blot: Positive WB detected in: NIH/3T3 whole cell lysate. All lanes: HLA-DQB1 antibody at 3μg/ml. Secondary: Goat polyclonal to rabbit IgG at 1/50000 dilution.WB
Western Blot: Positive WB detected in: NIH/3T3 whole cell lysate, RAW264.7 whole cell lysate. All lanes: HLA-DQB1 antibody at 1:2000. Secondary: Goat polyclonal to rabbit IgG at 1/50000 dilution.IHC
Immunohistochemistry of paraffin-embedded human lymph node tissue using HLA-DQB1 Antibody at dilution of 1:100.IHC
Immunohistochemistry of paraffin-embedded human skin tissue using HLA-DQB1 Antibody at dilution of 1:100| Product Name | Rabbit anti-HLA-DQB1 Polyclonal antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Immunogen | Recombinant Human HLA class II histocompatibility antigen, DQ beta 1 chain protein (128-175AA) |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | IHCWB |
| WB:1:200-1:3000 IHC:1:20-1:200 |
|
| Species Reactivity | HumanMouse |
| Concentration | 1mg/ml |
| Purification | Protein G |
| Gene Symbol | HLA-DQB2 |
|---|---|
| Gene Synonyms | DQB2 HLA-DXB HLA-DQB1 |
| Gene Full Name | major histocompatibility complex, class II, DQ beta 2 |
| Gene Summary | HLA-DQB2 belongs to the family of HLA class II beta chain paralogs. Class II molecules are heterodimers consisting of an alpha (DQA) and a beta chain (DQB), both anchored in the membrane. They play a central role in the immune system by presenting peptides derived from extracellular proteins. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages). Polymorphisms in the alpha and beta chains specify the peptide binding specificity, and typing for these polymorphisms is routinely done for bone marrow transplantation. However this gene, HLA-DQB2, is not routinely typed, as it is not thought to have an effect on transplantation. There is conflicting evidence in the literature and public sequence databases for the protein-coding capacity of HLA-DQB2. Because there is evidence of transcription and an intact ORF, HLA-DQB2 is represented in Entrez Gene and in RefSeq as a protein-coding locus. [provided by RefSeq, Oct 2010] |
| Alternative Names | CELIAC1 antibody DQ beta 1 chain antibody DQB1_HUMAN antibody HLA class II histocompatibility antigen antibody HLA class II histocompatibility antigen DQ beta 1 chain antibody HLA class II histocompatibility antigen DQ beta 2 chain antibody HLA DQB antibody HLA DQB1 antibody HLA-DQB1 antibody HLA-DQB2 antibody IDDM1 antibody Lymphocyte antigen antibody Major histocompatibility complex class II beta antibody Major histocompatibility complex class II DQ beta 1 antibody MHC class II antigen DQB1 antibody MHC class II antigen HLA DQ beta 1 antibody MHC class II DQ beta chain antibody MHC class II HLA DQ beta glycoprotein antibody MHC class2 antigen antibody MHC DQ beta antibody OTTHUMP00000029167 antibody OTTHUMP00000178569 antibody OTTHUMP00000178570 antibody OTTHUMP00000178571 antibody |
| Molecular Weight(MW) | 30 kDa |
| Cellular Localization | Cell membrane; Single-pass type I membrane protein. Endoplasmic reticulum membrane; Single-pass type I membrane protein. Golgi apparatus, trans-Golgi network membrane; Single-pass type I membrane protein. Endosome membrane; Single-pass type I membrane protein. Lysosome membrane; Single-pass type I membrane protein. Note=The MHC class II complex transits through a number of intracellular compartments in the endocytic pathway until it reaches the cell membrane for antigen presentation. |
WB
Western Blot: Positive WB detected in: NIH/3T3 whole cell lysate. All lanes: HLA-DQB1 antibody at 3μg/ml. Secondary: Goat polyclonal to rabbit IgG at 1/50000 dilution.
WB
Western Blot: Positive WB detected in: NIH/3T3 whole cell lysate, RAW264.7 whole cell lysate. All lanes: HLA-DQB1 antibody at 1:2000. Secondary: Goat polyclonal to rabbit IgG at 1/50000 dilution.
IHC
Immunohistochemistry of paraffin-embedded human lymph node tissue using HLA-DQB1 Antibody at dilution of 1:100.
IHC
Immunohistochemistry of paraffin-embedded human skin tissue using HLA-DQB1 Antibody at dilution of 1:100| Application Notes | WB:1:200-1:3000 IHC:1:20-1:200 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
| Storage Buffer | 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
