Recombinant Human Deoxyguanosine kinase, mitochondrial protein (40-277AA)
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
IHC
IHC:1:20-1:200
Species Reactivity
Human
Concentration
1mg/ml
Purification
Protein G
Target Information
Gene Symbol
DGUOK
Gene Synonyms
dGK NCPH NCPH1 PEOB4 MTDPS3
Gene Full Name
deoxyguanosine kinase
Gene Summary
In mammalian cells, the phosphorylation of purine deoxyribonucleosides is mediated predominantly by two deoxyribonucleoside kinases, cytosolic deoxycytidine kinase and mitochondrial deoxyguanosine kinase. The protein encoded by this gene is responsible for phosphorylation of purine deoxyribonucleosides in the mitochondrial matrix. In addition, this protein phosphorylates several purine deoxyribonucleoside analogs used in the treatment of lymphoproliferative disorders, and this phosphorylation is critical for the effectiveness of the analogs. Alternative splice variants encoding different protein isoforms have been described for this gene. [provided by RefSeq, Jul 2008]