Recombinant IL18 (Leu32~Asn192) expressed in E.coli.
Key Feature
Clonality
Monoclonal
Isotype
IgG1, k
Host Species
Mouse
Tested Applications
IHCWB
WB:0.01-2µg/mL IHC:5-20µg/mL
Species Reactivity
PigRabbit
Concentration
1mg/ml
Purification
Protein A/G
Target Information
Gene Symbol
IL18
Gene Synonyms
IGIF IL-18 IL-1g IL1F4
Gene Full Name
interleukin 18
Gene Summary
The protein encoded by this gene is a proinflammatory cytokine of the IL-1 family that is constitutively found as a precursor within the cytoplasm of a variety of cells including macrophages and keratinocytes. The inactive IL-18 precursor is processed to its active form by caspase-1, and is capable of stimulating interferon gamma production, and of regulating both T helper (Th) 1 and Th2 responses. This cytokine has been implicated in the injury of different organs, and in potentially fatal conditions characterized by a cytokine storm. In humans, IL-18 gene is located on chromosome 11. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Aug 2020]
Alternative Names
IGIF IL-1g IL1F4 IL1-F4 Interferon-Gamma-Inducing Factor Interleukin-1 Family Member 4 Iboctadekin Interleukin-1 Gamma
Molecular Weight(MW)
25 kDa
Application
WB
Figure. Western Blot; Sample:
Recombinant IL18, Rabbit.
IHC
DAB staining on IHC-P; Sample: Rabbit
Spleen Tissue; Primary Ab: 20µg/ml
Mouse Anti-Rabbit IL18 Antibody
Second Ab: 2µg/mL HRP-Linked
Caprine Anti-Mouse IgG Polyclonal
Antibody.
Application Notes
WB:0.01-2µg/mL IHC:5-20µg/mL
Additional Information
Form
Liquid
Storage Instructions
Avoid repeated freeze/thaw cycles.
Store at 4ºC for frequent use.
Aliquot and store at -20ºC for 24 months.
Storage Buffer
Supplied as solution form in 0.01M PBS, pH7.4, containing 0.05% Proclin-300,50% glycerol.