Recombinant fusion protein of human MBNL2. The exact sequence is proprietary.
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
WB
WB:1:500-1:2000
Species Reactivity
HumanMouse
Concentration
1mg/ml
Purification
Affinity purified
Target Information
Gene Symbol
MBNL2
Gene Synonyms
MBLL MBLL39 PRO2032
Gene Full Name
muscleblind like splicing regulator 2
Gene Summary
This gene is a member of the muscleblind protein family which was initially described in Drosophila melanogaster. This gene encodes a C3H-type zinc finger protein that modulates alternative splicing of pre-mRNAs. Muscleblind proteins bind specifically to expanded dsCUG RNA but not to normal size CUG repeats and may thereby play a role in the pathophysiology of myotonic dystrophy. Several alternatively spliced transcript variants have been described but the full-length natures of only some have been determined. [provided by RefSeq, Mar 2012]
Alternative Names
MBLL MBLL39 MLP1 Muscleblind-like protein 2 Muscleblind-like protein 1 Muscleblind-like protein-like Muscleblind-like protein-like 39
Molecular Weight(MW)
39; 40 kDa;(Observed band size: 39 kDa)
Cellular Localization
Cytoplasm,Nucleus.
Application
WB
Western blot analysis of MBNL2 expression in A549 (A), mouse brain (B) whole cell lysates.
Application Notes
WB:1:500-1:2000
Additional Information
Form
Liquid
Storage Instructions
Shipped at 4°C. Upon delivery aliquot and store at -20°C for one year. Avoid freeze/thaw cycles.
Storage Buffer
Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.