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Mouse Monoclonal antibody to MBNL2

Catalog Number:OM646395
OM646395
Discount Price
OM646395-100ul
100ul
Product Profile
Product Name Mouse Monoclonal antibody to MBNL2
Antibody Type Primary Antibodies
Immunogen raised against recombinant MBNL2 of human origin.
Key Feature
Clonality Monoclonal
Isotype IgG2b,k
Host Species Mouse
Tested Applications IHCWB
WB:1:100-1:1000
IHC:1:50-1:500
Species Reactivity HumanMouseRat
Concentration 0.1mg/ml
Purification Affinity purified
Target Information
Gene Symbol MBNL2
Gene Synonyms MBLL
MBLL39
PRO2032
Gene Full Name muscleblind like splicing regulator 2
Gene Summary This gene is a member of the muscleblind protein family which was initially described in Drosophila melanogaster. This gene encodes a C3H-type zinc finger protein that modulates alternative splicing of pre-mRNAs. Muscleblind proteins bind specifically to expanded dsCUG RNA but not to normal size CUG repeats and may thereby play a role in the pathophysiology of myotonic dystrophy. Several alternatively spliced transcript variants have been described but the full-length natures of only some have been determined. [provided by RefSeq, Mar 2012]
Molecular Weight(MW) 41 kDa
Cellular Localization Cytoplasm,Nucleus
Application

WB

MBNL2 Antibody (3B4): Western blot analysis of MBNL2 expression in whole-cell lysates of Caki-1 (A), SK-N-SH (B), HeLa (C), U-87 MG (D) cells and mouse brain tissue extract (E)

IHC

MBNL2 Antibody (3B4): Immunoperoxidase staining of formalin-fixed, paraffin-embedded human cerebral cortex tissue showing nuclear staining in neuronal cells and subsets of glial cells.

IHC

MBNL2 Antibody (3B4): Immunoperoxidase staining of formalin-fixed, paraffin-embedded human ovarian tissue, demonstrating nuclear and cytoplasmic staining in ovarian stromal cells.
Application Notes WB:1:100-1:1000
IHC:1:50-1:500
Additional Information
Form Liquid
Storage Instructions Store at 4° C, **DO NOT FREEZE**. Stable for one year from the date of shipment. Non-hazardous. No MSDS required.
Storage Buffer Each vial contains 200 µg IgG2b kappa light chain in 1.0 ml of PBS with < 0.1% sodium azide and 0.1% gelatin.
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