WB
Figure.Western Blot;Sample: Recombinant TLR3, Human.| Product Name | Monoclonal Antibody to Toll Like Receptor 3 (TLR3) |
|---|---|
| Antibody Type | Primary Antibodies |
| Immunogen | Recombinant TLR3 (Leu404~Leu532) expressed in E.coli. |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG1, k |
| Host Species | Mouse |
| Tested Applications | WB |
| WB:0.01-2µg/mL |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Purification | Protein A/G |
| Gene Symbol | TLR3 |
|---|---|
| Gene Synonyms | CD283 IIAE2 IMD83 |
| Gene Full Name | toll like receptor 3 |
| Gene Summary | The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This receptor is most abundantly expressed in placenta and pancreas, and is restricted to the dendritic subpopulation of the leukocytes. It recognizes dsRNA associated with viral infection, and induces the activation of NF-kappaB and the production of type I interferons. It thus plays a role in host defense against multiple viruses. [provided by RefSeq, Jul 2021] |
| Alternative Names | CD283 |
| Molecular Weight(MW) | 20 kDa |
| Cellular Localization | Endoplasmic reticulum,Endosome,Membrane. |
WB
Figure.Western Blot;Sample: Recombinant TLR3, Human.| Application Notes | WB:0.01-2µg/mL |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Avoid repeated freeze/thaw cycles. Store at 4ºC for frequent use. Aliquot and store at -20ºC for 24 months. |
| Storage Buffer | Supplied as solution form in 0.01M PBS, pH7.4, containing 0.05% Proclin-300, 50% glycerol |
