Synthesized peptide derived from part region of human protein. AA range:39-139.
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
WB
WB:1:500-1:2000
Species Reactivity
HumanMouseRat
Concentration
1mg/ml
Purification
Affinity purified
Target Information
Gene Symbol
VAMP7
Gene Synonyms
SYBL1 TIVAMP VAMP-7 TI-VAMP
Gene Full Name
vesicle associated membrane protein 7
Gene Summary
This gene encodes a transmembrane protein that is a member of the soluble N-ethylmaleimide-sensitive factor attachment protein receptor (SNARE) family. The encoded protein localizes to late endosomes and lysosomes and is involved in the fusion of transport vesicles to their target membranes. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Jun 2010]
Molecular Weight(MW)
24 kDa
Cellular Localization
Cytoplasmic vesicle , secretory vesicle membrane ; Single-pass type IV membrane protein . Golgi apparatus , trans-Golgi network membrane ; Single-pass type IV membrane protein . Late endosome membrane ; Single-pass type IV membrane protein . Lysosome membrane ; Single-pass type IV membrane protein . Endoplasmic reticulum membrane ; Single-pass type IV membrane protein . Cytoplasmic vesicle , phagosome membrane ; Single-pass type IV membrane protein . Cell junction , synapse , synaptosome . In immature neurons expression is localized in vesicular structures in axons and dendrites while in mature neurons it is localized to the somatodendritic region. Colocalizes with LAMP1 in kidney cells. Localization to the endoplasmic reticulum membrane was observed in the intestine but not in liver or kidney (By similarity) . .
Application
WB
Western blot analysis of lysates from U2OS cells, primary antibody was diluted at 1:1000, 4℃ over night.
Application Notes
WB:1:500-1:2000
Additional Information
Form
Liquid
Storage Instructions
-15°C to -25°C/1 year (Do not lower than -25°C).
Storage Buffer
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.