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Fascin Rabbit mAb

Catalog Number:OM647283
OM647283
Discount Price
OM647283-100ul
100ul
OM647283-50ul
50ul
Product Profile
Product Name Fascin Rabbit mAb
Antibody Type Primary Antibodies
Immunogen The specific immunogen used to produce this antibody is proprietary information.
Key Feature
Clonality Monoclonal
Isotype IgG,K
Host Species Rabbit
Tested Applications IF-PIHCWB
WB:1:10000-1:20000
IHC:1:1000-1:5000
IF-P:1:200-1:1000
Species Reactivity HumanMouseRat
Concentration 1mg/ml
Purification Protein A
Target Information
Gene Symbol FSCN1
Gene Synonyms HSN
SNL
p55
Gene Full Name fascin actin-bundling protein 1
Gene Summary This gene encodes a member of the fascin family of actin-binding proteins. Fascin proteins organize F-actin into parallel bundles, and are required for the formation of actin-based cellular protrusions. The encoded protein plays a critical role in cell migration, motility, adhesion and cellular interactions. Expression of this gene is known to be regulated by several microRNAs, and overexpression of this gene may play a role in the metastasis of multiple types of cancer by increasing cell motility. Expression of this gene is also a marker for Reed-Sternberg cells in Hodgkin's lymphoma. A pseudogene of this gene is located on the long arm of chromosome 15. [provided by RefSeq, Sep 2011]
Molecular Weight(MW) 54 kDa
Cellular Localization Cytoplasmic.
Application

WB

Various whole cell lysates were separated by 4-20% SDS-PAGE, and the membrane was blotted with anti-Fascin antibody. The HRP-conjugated Goat anti-Rabbit IgG (H + L) antibody was used to detect the antibody.

IHC

Human tonsil was stained with anti-Fascin rabbit antibody.

IHC

Rat colon was stained with anti-Fascin rabbit antibody.

IF-P

Fluorescence immunohistochemical analysis of Human hepatocellular carcinoma.
Application Notes WB:1:10000-1:20000
IHC:1:1000-1:5000
IF-P:1:200-1:1000
Additional Information
Form Liquid
Storage Instructions -15°C to -25°C/1 year (Do not lower than -25°C).
Storage Buffer PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA.
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