raised against amino acids
1-270 mapping at the N-terminus of Cosmc of human origin.
Key Feature
Clonality
Monoclonal
Isotype
IgG1, k
Host Species
Mouse
Tested Applications
WB
WB:1:100-1:1000
Species Reactivity
Human
Concentration
0.1mg/ml
Purification
Affinity purified
Target Information
Gene Symbol
C1GALT1C1
Gene Synonyms
TNPS AHUS8 COSMC MST143 C1GALT2 HSPC067 C38H2-L1
Gene Full Name
C1GALT1 specific chaperone 1
Gene Summary
This gene encodes a type II transmembrane protein that is similar to the core 1 beta1,3-galactosyltransferase 1, which catalyzes the synthesis of the core-1 structure, also known as Thomsen-Friedenreich antigen, on O-linked glycans. This gene product lacks the galactosyltransferase activity itself, but instead acts as a molecular chaperone required for the folding, stability and full activity of the core 1 beta1,3-galactosyltransferase 1. Mutations in this gene have been associated with Tn syndrome. Alternatively spliced transcript variants encoding the same protein have been identified. [provided by RefSeq, Dec 2009]
Molecular Weight(MW)
36 kDa
Cellular Localization
Membrane.
Application
WB
Cosmc Antibody : Western blot analysis of Cosmc expression in MIA PaCa-2 (A), HEK293 (B), Hep G2 (C) and HeLa (D) whole cell lysates.
Application Notes
WB:1:100-1:1000
Additional Information
Form
Liquid
Storage Instructions
Store at 4° C, **DO NOT FREEZE**. Stable for one year from the date of
shipment. Non-hazardous. No MSDS required.
Storage Buffer
Each vial contains 200 µg IgG1 kappa light chain in 1.0 ml of PBS with < 0.1%
sodium azide and 0.1% gelatin.