WB
Western blot. All lanes: LEFTY2 antibody at 2μg/ml + A431 whole cell lysate. Secondary Goat polyclonal to rabbit IgG at 1/10000 dilution.IHC
Immunohistochemistry of paraffin-embedded human endometrial cancer using LEFTY2 Antibody at dilution of 1: 100.| Product Name | Rabbit anti-LEFTY2 Polyclonal antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Immunogen | Recombinant Human Left-right determination factor 2 protein (57-366AA). |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | IHCWB |
| WB:1:1000-1:5000 IHC:1:20-1:200 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | LEFTY2 |
|---|---|
| Gene Synonyms | EBAF LEFTA TGFB4 LEFTYA |
| Gene Full Name | left-right determination factor 2 |
| Gene Summary | This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate the mature protein, which plays a role in left-right asymmetry determination of organ systems during development. The protein may also play a role in endometrial bleeding. Mutations in this gene have been associated with left-right axis malformations, particularly in the heart and lungs. Some types of infertility have been associated with dysregulated expression of this gene in the endometrium. This gene is closely linked to both a related family member and a related pseudogene. This gene encodes multiple isoforms that may undergo similar proteolytic processing. [provided by RefSeq, Aug 2016] |
| Alternative Names | EBAF antibody Endometrial bleeding associated factor (left right determination factor A transforming growth factor beta superfamily) antibody Endometrial bleeding associated factor antibody Endometrial bleeding-associated factor antibody Left right determination factor 2 antibody Left right determination factor A antibody Left-right determination factor 2 antibody Left-right determination factor A antibody LEFTA antibody LEFTY 2 antibody LEFTY2 antibody LEFTYA antibody LFTY2 transforming growth factor beta -4 antibody LFTY2 mouse homolog of antibody LFTY2_HUMAN antibody MGC46222 antibody Protein lefty 2 antibody Protein lefty A antibody Protein lefty-2 antibody Protein lefty-A antibody Protein lefty2 antibody PSEC0024 antibody TGF beta 4 antibody TGF-beta-4 antibody TGFB4 antibody Transforming growth factor beta 4 antibody Transforming growth factor beta-4 antibody |
| Molecular Weight(MW) | 41, 38 kDa(Observed band size: 41 kDa) |
| Cellular Localization | Secreted. |
WB
Western blot. All lanes: LEFTY2 antibody at 2μg/ml + A431 whole cell lysate. Secondary Goat polyclonal to rabbit IgG at 1/10000 dilution.
IHC
Immunohistochemistry of paraffin-embedded human endometrial cancer using LEFTY2 Antibody at dilution of 1: 100.| Application Notes | WB:1:1000-1:5000 IHC:1:20-1:200 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
| Storage Buffer | PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
