IHC
Hepatocyte Specific Antigen Antibody : Hepatocyte Specific Antigen Antibody. Immunoperoxidase staining of formalin fixed, paraffin-embedded mouse liver tissue showing cytoplasmic staining of hepatocytes.IHC
Hepatocyte Specific Antigen Antibody : Hepatocyte Specific Antigen Antibody. Immunoperoxidase staining of formalin fixed, paraffin-embedded rat liver tissue showing cytoplasmic staining of hepatocytes.IHC
Hepatocyte Specific Antigen Antibody : Hepatocyte Specific Antigen Antibody. Immunoperoxidase staining of formalin fixed, paraffin-embedded human liver tissue showing cytoplasmic staining of hepatocytes.| Product Name | Mouse Monoclonal antibody to Hepatocyte Specific Antigen |
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| Antibody Type | Primary Antibodies |
| Immunogen | raised against liver extract of human origin. |
| Clonality | Monoclonal |
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| Isotype | IgG1, k |
| Host Species | Mouse |
| Tested Applications | IHC |
| IHC:1:50-1:500 |
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| Species Reactivity | Human |
| Concentration | 0.1mg/ml |
| Purification | Affinity purified |
| Function | Hepatocyte Specific Antigen, also called Hepatocyte Paraffin 1 or Hep Par 1, localizes to the mitochondria of hepatocytes. It is a sensitive marker for diag nosing hepatocellular carcinomas (HCC) in humans and dogs and distinguish ing them from metastatic carcinomas and cholangiocarcinomas. Strong expres sion of the Hepatocyte Specific Antigen correlates with smaller tumors and longer patient survival. HCCs occur primarily in the stomach, but they are also found in many other organs. The Hepatocyte Specific Antigen may also be a useful marker for intestinal metaplasia. A very small percentage of HCCs do not contain the Hepatocyte Specific Antigen, and this may be associated with an alternative mechanism of hepatocarcinogenesis in its early stages. To a lesser extent, the Hepatocyte Specific Antigen is also found in gastric carcinomas as well as a few other nonhepatic tumors. |
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IHC
Hepatocyte Specific Antigen Antibody : Hepatocyte Specific Antigen Antibody. Immunoperoxidase staining of formalin fixed, paraffin-embedded mouse liver tissue showing cytoplasmic staining of hepatocytes.
IHC
Hepatocyte Specific Antigen Antibody : Hepatocyte Specific Antigen Antibody. Immunoperoxidase staining of formalin fixed, paraffin-embedded rat liver tissue showing cytoplasmic staining of hepatocytes.
IHC
Hepatocyte Specific Antigen Antibody : Hepatocyte Specific Antigen Antibody. Immunoperoxidase staining of formalin fixed, paraffin-embedded human liver tissue showing cytoplasmic staining of hepatocytes.| Application Notes | IHC:1:50-1:500 |
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| Form | Liquid |
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| Storage Instructions | Store at 4° C, **DO NOT FREEZE**. Stable for one year from the date of shipment. Non-hazardous. No MSDS required. |
| Storage Buffer | Each vial contains 200 µg IgG1 kappa light chain in 1.0 ml of PBS with < 0.1% sodium azide and 0.1% gelatin. |
