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Mitofusin 2 Rabbit mAb

Catalog Number:OM647474
OM647474
Discount Price
OM647474-100ul
100ul
OM647474-50ul
50ul
Product Profile
Product Name Mitofusin 2 Rabbit mAb
Antibody Type Primary Antibodies
Immunogen A synthesized peptide derived from human Mitofusin 2.
Key Feature
Clonality Monoclonal
Isotype IgG
Host Species Rabbit
Tested Applications ICC/IFIHCWB
WB:1:1000-1:2000
IHC:1:100-1:200
ICC/IF:1:50-1:200
Species Reactivity HumanMouseRat
Concentration 1mg/ml
Purification Affinity purified
Target Information
Gene Symbol MFN2
Gene Synonyms HSG
MSL
MARF
CMT2A
CPRP1
CMT2A2
HMSN6A
CMT2A2A
CMT2A2B
Gene Full Name mitofusin 2
Gene Summary This gene encodes a mitochondrial membrane protein that participates in mitochondrial fusion and contributes to the maintenance and operation of the mitochondrial network. This protein is involved in the regulation of vascular smooth muscle cell proliferation, and it may play a role in the pathophysiology of obesity. Mutations in this gene cause Charcot-Marie-Tooth disease type 2A2, and hereditary motor and sensory neuropathy VI, which are both disorders of the peripheral nervous system. Defects in this gene have also been associated with early-onset stroke. Two transcript variants encoding the same protein have been identified. [provided by RefSeq, Jul 2008]
Alternative Names CMT2A2
CMT2A
CPRP1
MFN2
Hyperplasia suppressor
MARF
Mitofusin 2
HSG
Mitofusin-2
Molecular Weight(MW) 86 kDa(Observed band size: 80 kDa)
Cellular Localization Membrane,Mitochondrion,Mitochondrion outer membrane.
Application

WB

All lanes use the Antibody at 1:1K dilution for 1 hour at room temperature.

IHC

Immunohistochemical analysis of paraffin-embedded human breast carcinoma, using Mitofusin 2 Antibody.

ICC/IF

Immunofluorescent analysis using the Antibody at 1:50 dilution.
Application Notes WB:1:1000-1:2000
IHC:1:100-1:200
ICC/IF:1:50-1:200
Additional Information
Form Liquid
Storage Instructions Store at +4°C for short term. Store at -20°C for long term. Avoid freeze/thaw cycle.
Storage Buffer Rabbit IgG in 10mM phosphate buffered saline , pH 7.4, 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol.
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