IHC
Immunohistochemical analysis of paraffin-embedded Human bladder cancer tissues using STIM1 antibody with DAB staining.IHC
Immunohistochemical analysis of paraffin-embedded Human breast cancer tissues using STIM1 antibody with DAB staining.IHC
Immunohistochemical analysis of paraffin-embedded Human cervical cancer tissues using STIM1 antibody with DAB staining.IHC
Immunohistochemical analysis of paraffin-embedded Human ovarian cancer tissues using STIM1 antibody with DAB staining.WB
Western blot analysis using STIM1 antibody against A549(1),Nih3t3(2),Cos-7(3),C2C12(4),Hek293(5),Mcf-7(6),Pc-12(7),Jurkat(8),Raji(9) cell .WB
Western blot analysis using STIM1 antibody against Mouse skin tissue(1),Mouse kidney tissue(2),Mouse brain tissue(3),Mouse liver tissue(4),Mouse lung tissue(5),Mouse spleen tissue(6),Mouse stomach tissue(7),Mouse heart tissue(8),Rat brain tissue(9),Rat liver tissue(10),Rat stomach tissue(11),Rat testes tissue(12) .| Product Name | Anti-STIM1 antibody-HRP |
|---|---|
| Antibody Type | Primary Antibodies |
| Immunogen | Polypeptide |
| Conjugation | HRP |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIHC |
| WB:1:200-1:2000 IHC:1:100-1:1000 |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Protein A |
| Gene Symbol | STIM1 |
|---|---|
| Gene Synonyms | GOK SIM STIM 1 Stim1 stromal interaction molecule 1 STIM1L |
| Gene Full Name | stromal interaction molecule 1 |
| Gene Summary | This gene encodes a type 1 transmembrane protein that mediates Ca2+ influx after depletion of intracellular Ca2+ stores by gating of store-operated Ca2+ influx channels (SOCs). It is one of several genes located in the imprinted gene domain of 11p15.5, an important tumor-suppressor gene region. Alterations in this region have been associated with the Beckwith-Wiedemann syndrome, Wilms tumor, rhabdomyosarcoma, adrenocrotical carcinoma, and lung, ovarian, and breast cancer. This gene may play a role in malignancies and disease that involve this region, as well as early hematopoiesis, by mediating attachment to stromal cells. Mutations in this gene are associated with fatal classic Kaposi sarcoma, immunodeficiency due to defects in store-operated calcium entry (SOCE) in fibroblasts, ectodermal dysplasia and tubular aggregate myopathy. This gene is oriented in a head-to-tail configuration with the ribonucleotide reductase 1 gene (RRM1), with the 3' end of this gene situated 1.6 kb from the 5' end of the RRM1 gene. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, May 2013] |
| Molecular Weight(MW) | 77kDa(observed:100kDa) |
| Source | Rabbit |
| Cellular Localization | Cell membrane, Endoplasmic reticulum membrane, Cytoplasm, Sarcoplasmic reticulum |
| SwissProt ID | Q13586 |
|---|
IHC
Immunohistochemical analysis of paraffin-embedded Human bladder cancer tissues using STIM1 antibody with DAB staining.
IHC
Immunohistochemical analysis of paraffin-embedded Human breast cancer tissues using STIM1 antibody with DAB staining.
IHC
Immunohistochemical analysis of paraffin-embedded Human cervical cancer tissues using STIM1 antibody with DAB staining.
IHC
Immunohistochemical analysis of paraffin-embedded Human ovarian cancer tissues using STIM1 antibody with DAB staining.
WB
Western blot analysis using STIM1 antibody against A549(1),Nih3t3(2),Cos-7(3),C2C12(4),Hek293(5),Mcf-7(6),Pc-12(7),Jurkat(8),Raji(9) cell .
WB
Western blot analysis using STIM1 antibody against Mouse skin tissue(1),Mouse kidney tissue(2),Mouse brain tissue(3),Mouse liver tissue(4),Mouse lung tissue(5),Mouse spleen tissue(6),Mouse stomach tissue(7),Mouse heart tissue(8),Rat brain tissue(9),Rat liver tissue(10),Rat stomach tissue(11),Rat testes tissue(12) .| Application Notes | WB:1:200-1:2000 IHC:1:100-1:1000 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle. |
| Storage Buffer | Purified antibody in PBS with 0.05% sodium azide. |
