ELISA
Coat the plate with immunizing antigen.Blue line： Immune serum; Orange line: Pre-immune serum.| Product Name | Anti-ATRX antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Immunogen | Polypeptide |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | ELISA |
| ELISA:1:1000-1:10000 |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Protein A |
| Gene Symbol | ATRX |
|---|---|
| Gene Synonyms | 4833408C14Rik ATR2 DXHXS6677E HP1-BP38 Hp1bp2 Hp1bp38 JMS MRX52 MRXS3 RAD54 RAD54L XH2 XNP ZNF-HX |
| Gene Full Name | ATRX chromatin remodeler |
| Gene Summary | The protein encoded by this gene contains an ATPase/helicase domain, and thus it belongs to the SWI/SNF family of chromatin remodeling proteins. This protein is found to undergo cell cycle-dependent phosphorylation, which regulates its nuclear matrix and chromatin association, and suggests its involvement in the gene regulation at interphase and chromosomal segregation in mitosis. Mutations in this gene are associated with X-linked syndromes exhibiting cognitive disabilities as well as alpha-thalassemia (ATRX) syndrome. These mutations have been shown to cause diverse changes in the pattern of DNA methylation, which may provide a link between chromatin remodeling, DNA methylation, and gene expression in developmental processes. Multiple alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2017] |
| Alternative Names | ATP-dependent helicase ATRX ATRX helicase 2 helicase II heterochromatin protein 2 HP1 alpha-interacting protein pABP-2 putative ATPase and helicase RP5-875J14.1 transcriptional regulator ATRX transcriptional regulator ATRX-like X-linked helicase II X-linked nuclear protein |
| Molecular Weight(MW) | 282kDa |
| Source | Rabbit |
| Cellular Localization | Nucleus;Chromosome, telomere;Nucleus, PML body |
| SwissProt ID | P46100 |
|---|
ELISA
Coat the plate with immunizing antigen.Blue line： Immune serum; Orange line: Pre-immune serum.| Application Notes | ELISA:1:1000-1:10000 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle. |
| Storage Buffer | Purified antibody in PBS with 0.05% PC300. |
