| Product Name | Anti-AICAR transformylase antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Immunogen | Polypeptide |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | ELISA |
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Protein A |
| Gene Symbol | ATIC |
|---|---|
| Gene Synonyms | 2610509C24Rik AICAR AICARFT HEL-S-70p IMPCHASE PURH |
| Gene Full Name | 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase |
| Gene Summary | This gene encodes a bifunctional protein that catalyzes the last two steps of the de novo purine biosynthetic pathway. The N-terminal domain has phosphoribosylaminoimidazolecarboxamide formyltransferase activity, and the C-terminal domain has IMP cyclohydrolase activity. A mutation in this gene results in AICA-ribosiduria. [provided by RefSeq, Sep 2009] |
| Alternative Names | 5-aminoimidazole-4-carboxamide-1-beta-D-ribonucleotide transformylase/inosinicase AICAR formyltransferase/IMP cyclohydrolase bifunctional enzyme AICAR transformylase/inosine monophosphate cyclohydrolase bifunctional purine biosynthesis protein PURH bifunctional purine biosynthesis protein PURH-like epididymis secretory sperm binding protein Li 70p phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase |
| Molecular Weight(MW) | 64kDa |
| Source | Rabbit |
| Cellular Localization | Cytoplasm, cytosol |
| SwissProt ID | P31939 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle. |
| Storage Buffer | Purified antibody in PBS with 0.05% PC300. |
