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Mouse Monoclonal antibody to AICAR transformylase

Catalog Number:OM645107
OM645107
Discount Price
OM645107-100ul
100ul
Product Profile
Product Name Mouse Monoclonal antibody to AICAR transformylase
Antibody Type Primary Antibodies
Immunogen Amino acids 582-592 of AICAR transformylase of human origin
Key Feature
Clonality monoclonal
Isotype IgG1, k
Host Species Mouse
Tested Applications WB
WB:1:100-1:1000
Species Reactivity HumanMouseRat
Concentration 0.2mg/ml
Purification Affinity purified
Target Information
Gene Symbol ATIC
Gene Synonyms PURH
AICAR
AICARFT
IMPCHASE
HEL-S-70p
Gene Full Name 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase
Gene Summary This gene encodes a bifunctional protein that catalyzes the last two steps of the de novo purine biosynthetic pathway. The N-terminal domain has phosphoribosylaminoimidazolecarboxamide formyltransferase activity, and the C-terminal domain has IMP cyclohydrolase activity. A mutation in this gene results in AICA-ribosiduria. [provided by RefSeq, Sep 2009]
Molecular Weight(MW) 65 kDa
Application

WB

Western blot analysis of AICAR convertase expression in HeLa(A), HCT-116 (B), CCRF-CEM (C), Hep G2 (D),A-431 (E), and HEK293 (F) whole cell lysates
Application Notes WB:1:100-1:1000
Additional Information
Form Liquid
Storage Instructions Store at 4° C, **DO NOT FREEZE**. Stable for one year from the date of shipment. Non-hazardous. No MSDS required.
Storage Buffer Each vial contains 200 µg IgG1 kappa light chain in 1.0 ml of PBS with < 0.1% sodium azide and 0.1% gelatin.
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