| Product Name | Anti-FKBP1A antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Immunogen | Polypeptide |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | ELISA |
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Protein A |
| Gene Symbol | FKBP1A |
|---|---|
| Gene Synonyms | Fkbp FKBP-12 FKBP-1A FKBP1 FKBP12 Fkbp2 PKC12 PKCI2 PPIASE |
| Gene Full Name | FKBP prolyl isomerase 1A |
| Gene Summary | The protein encoded by this gene is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. The protein is a cis-trans prolyl isomerase that binds the immunosuppressants FK506 and rapamycin. It interacts with several intracellular signal transduction proteins including type I TGF-beta receptor. It also interacts with multiple intracellular calcium release channels, and coordinates multi-protein complex formation of the tetrameric skeletal muscle ryanodine receptor. In mouse, deletion of this homologous gene causes congenital heart disorder known as noncompaction of left ventricular myocardium. Multiple alternatively spliced variants, encoding the same protein, have been identified. The human genome contains five pseudogenes related to this gene, at least one of which is transcribed. [provided by RefSeq, Sep 2008] |
| Alternative Names | 12 kDa FK506-binding protein 12 kDa FKBP calstabin-1 EC 5.2.1.8 FK506 binding protein 12 FK506 binding protein 1a FK506 binding protein 1A 12kDa FK506 binding protein 2 (13 kDa) FK506 binding protein12 FK506-binding protein (FKBP) FK506-binding protein 1 FK506-binding protein 1 (12kD) FK506-binding protein 12 FK506-binding protein 1A FK506-binding protein T-cell 12-kD FKBP-12 FKBP-1A FKBP12-Exip3 FKBP1A immunophilin FKBP12 PPIase FKBP1A protein kinase C inhibitor 2 rotamase |
| Molecular Weight(MW) | 11kDa |
| Source | Rabbit |
| Cellular Localization | Cytoplasm, cytosol;Sarcoplasmic reticulum membrane |
| SwissProt ID | P62942 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle. |
| Storage Buffer | Purified antibody in PBS with 0.05% PC300. |
