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Mouse Monoclonal antibody to Pax(D-7)

Catalog Number:OM670520
OM670520
Discount Price
OM670520-100ul
100ul
Product Profile
Product Name Mouse Monoclonal antibody to Pax(D-7)
Antibody Type Primary Antibodies
Immunogen raised against amino acids 72-150 of Pax-2 of human origin
Key Feature
Clonality Monoclonal
Isotype IgG2a,k
Host Species Mouse
Tested Applications IHCWB
WB:1:100-1:1000
IHC:1:50-1:500
Species Reactivity Human
Concentration 0.1mg/ml
Purification Affinity purified
Target Information
Gene Symbol Pax-1, Pax-2, Pax-3, Pax-5, Pax-6, Pax-7, Pax-8 and Pax-9
Gene Synonyms Pax1
Gene Full Name paired box
Gene Summary Enables DNA-binding transcription activator activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in positive regulation of transcription by RNA polymerase II and sclerotome development. Acts upstream of or within several processes, including alpha-beta T cell differentiation; parathyroid gland development; and thymus development. Predicted to be located in nucleus. Predicted to be part of transcription regulator complex. Is expressed in several structures, including branchial pouch; central nervous system; embryo mesenchyme; foregut diverticulum; and musculoskeletal system. Human ortholog(s) of this gene implicated in branchiootorenal syndrome. Orthologous to human PAX1 (paired box 1). [provided by Alliance of Genome Resources, Jul 2025]
Molecular Weight(MW) 44-50 kDa
Application

WB

Western blot analysis of Pax expression in TF-1 (A), BYDP (B), M1 (C) and P19 (D) whole cell lysates and HEL 92.1.7 nuclear extract (E).

IHC

Immunoperoxidase staining of formalin fixed, paraffin-embedded human parathyroid (A) and human thyroid (B) gland tissue showing nuclear and cytoplasmic staining of glandular cells.
Application Notes WB:1:100-1:1000
IHC:1:50-1:500
Additional Information
Form Liquid
Storage Instructions Store at 4° C, **DO NOT FREEZE**. Stable for one year from the date of shipment. Non-hazardous. No MSDS required.
Storage Buffer Each vial contains 200 µg IgG2a kappa light chain in 1.0 ml of PBS with < 0.1% sodium azide and 0.1% gelatin. Also available as TransCruz reagent for Gel Supershift and ChIP applications, 200 µg/0.1 ml.
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