WB
Various whole cell lysates were separated by 4-20% SDS-PAGE, and the membrane was blotted with anti-Granzyme B antibody. The HRP-conjugated Goat anti-Rabbit IgG(H + L) antibody was used to detect the antibody. Lane 1: Karpas-299 Lane 2: NK92.IHC
Human spleen was stained with anti-Granzyme B rabbit antibody.| Product Name | Granzyme B Rabbit mAb |
|---|---|
| Antibody Type | Primary Antibodies |
| Clonality | monoclonal |
|---|---|
| Isotype | IgG,K |
| Host Species | Rabbit |
| Tested Applications | IHCWB |
| WB:1:2000-1:10000 IHC:1:1000-1:4000 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Purification | Protein A |
| Gene Symbol | GZMB |
|---|---|
| Gene Synonyms | C11 HLP CCPI CGL1 CSPB SECT CGL-1 CSP-B CTLA1 CTSGL1 |
| Gene Full Name | granzyme B |
| Gene Summary | This gene encodes a member of the granzyme subfamily of proteins, part of the peptidase S1 family of serine proteases. The encoded preproprotein is secreted by natural killer (NK) cells and cytotoxic T lymphocytes (CTLs) and proteolytically processed to generate the active protease, which induces target cell apoptosis. This protein also processes cytokines and degrades extracellular matrix proteins, and these roles are implicated in chronic inflammation and wound healing. Expression of this gene may be elevated in human patients with cardiac fibrosis. [provided by RefSeq, Sep 2016] |
| Alternative Names | Granzyme B C11 CTLA-1 Cathepsin G-like 1 CTSGL1 Cytotoxic T-lymphocyte proteinase 2 Lymphocyte protease Fragmentin-2 Granzyme-2 Human lymphocyte protein HLP SECT T-cell serine protease 1-3E |
| Molecular Weight(MW) | 28kDa(Observed MW 37kDa) |
| Cellular Localization | Lysosome. |
WB
Various whole cell lysates were separated by 4-20% SDS-PAGE, and the membrane was blotted with anti-Granzyme B antibody. The HRP-conjugated Goat anti-Rabbit IgG(H + L) antibody was used to detect the antibody. Lane 1: Karpas-299 Lane 2: NK92.
IHC
Human spleen was stained with anti-Granzyme B rabbit antibody.| Application Notes | WB:1:2000-1:10000 IHC:1:1000-1:4000 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Storage Buffer | PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA |
