| Gene Symbol |
PKD2
|
| Gene Synonyms |
PC2, PKD4, Pc-2, APKD2, TRPP2 |
| Gene Full Name |
polycystin 2, transient receptor potential cation channel |
| Gene Summary |
This gene encodes a member of the polycystin protein family. The encoded protein is a multi-pass membrane protein that functions as a calcium permeable cation channel, and is involved in calcium transport and calcium signaling in renal epithelial cells. This protein interacts with polycystin 1, and they may be partners in a common signaling cascade involved in tubular morphogenesis. Mutations in this gene are associated with autosomal dominant polycystic kidney disease type 2. [provided by RefSeq, Mar 2011] |
| Alternative Names |
B dynamin D100 DNM 1 DNM DNM1 DYN1_HUMAN Dynamin Dynamin-1 Dynamin1
|
| Molecular Weight(MW) |
97kDa |
| Cellular Localization |
Cytoplasm. Cytoplasm>Cytoskeleton. |