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Anti-Phospho-lin28b (Ser203) antibody

Catalog Number:OM682194
OM682194
Discount Price
OM682194-100ul
100ul
Product Profile
Product Name Anti-Phospho-lin28b (Ser203) antibody
Antibody Type Primary Antibodies
Immunogen Synthetic peptide conjugated with KLH.
Modification p-Ser203
Key Feature
Clonality Polyclonal
Isotype IgG
Host Species Rabbit
Tested Applications ELISA
Concentration 1mg/ml
Purification Affinity purified
Target Information
Gene Symbol LIN28B
Gene Synonyms CSDD2
Gene Full Name lin-28 RNA binding posttranscriptional regulator B
Gene Summary The protein encoded by this gene belongs to the lin-28 family, which is characterized by the presence of a cold-shock domain and a pair of CCHC zinc finger domains. This gene is highly expressed in testis, fetal liver, placenta, and in primary human tumors and cancer cell lines. It is negatively regulated by microRNAs that target sites in the 3' UTR, and overexpression of this gene in primary tumors is linked to the repression of let-7 family of microRNAs and derepression of let-7 targets, which facilitates cellular transformation. [provided by RefSeq, Jun 2012]
Alternative Names CSDD 2
CSDD2
FLJ16517
Lin 28 homolog B (C. elegans)
Lin 28.2
Lin-28B
LIN28B
LN28B_HUMAN
Protein lin-28 homolog B
Molecular Weight(MW) 27 kDa
Cellular Localization Cytoplasm, Nucleus.
Database Links
SwissProt ID Q6ZN17
Application

ELISA

Coat the plate with 100ng immunizing antigen. The phospho-specific antibody,pbs only can specifically recognize phosphorylated peptide and enable quantitative detection over a wide dynamic range. Non-phosphorylated peptide shows no cross-reactivity, and the background signal remains low, indicating that the phospho-specific antibody,pbs only possesses high specificity and an excellent signal-to-noise ratio. Black line: phospho-peptide; Rad line: non-phospho peptide
Additional Information
Form Liquid
Storage Instructions Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Storage Buffer Purified antibody in PBS with 0.05% sodium azide,40% Glycerol.
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