| Gene Symbol |
KDR
|
| Gene Synonyms |
FLK1 CD309 VEGFR VEGFR2 |
| Gene Full Name |
kinase insert domain receptor |
| Gene Summary |
Vascular endothelial growth factor (VEGF) is a major growth factor for endothelial cells. This gene encodes one of the two receptors of the VEGF. This receptor, known as kinase insert domain receptor, is a type III receptor tyrosine kinase. It functions as the main mediator of VEGF-induced endothelial proliferation, survival, migration, tubular morphogenesis and sprouting. The signalling and trafficking of this receptor are regulated by multiple factors, including Rab GTPase, P2Y purine nucleotide receptor, integrin alphaVbeta3, T-cell protein tyrosine phosphatase, etc.. Mutations of this gene are implicated in infantile capillary hemangiomas. [provided by RefSeq, May 2009] |
| Alternative Names |
CD309 antibody
CD309 antigen antibody
EC 2.7.10.1 antibody
Fetal liver kinase 1 antibody
FLK-1 antibody
FLK1 antibody
FLK1 mouse homolog of antibody
Kdr antibody
Kinase insert domain receptor (a type III receptor tyrosine kinase) antibody
Kinase insert domain receptor antibody
KRD1 antibody
Ly73 antibody
Protein tyrosine kinase receptor FLK1 antibody
Protein-tyrosine kinase receptor flk-1 antibody
soluble VEGFR2 antibody
Tyrosine kinase growth factor receptor antibody
Vascular endothelial growth factor receptor 2 antibody
VEGFR 2 antibody
VEGFR antibody
VEGFR-2 antibody
VEGFR2 antibody
VGFR2_HUMAN antibody |
| Molecular Weight(MW) |
152 kDa |
| Cellular Localization |
Cell junction,Cell membrane,Cytoplasm,Cytoplasmic vesicle,Endoplasmic reticulum,Endosome,Membrane,Nucleus,Secreted. |