| Gene Symbol |
AURKC
|
| Gene Synonyms |
AIE2 AIK3 ARK3 AurC SPGF5 STK13 HEL-S-90 aurora-C |
| Gene Full Name |
aurora kinase C |
| Gene Summary |
This gene encodes a member of the Aurora subfamily of serine/threonine protein kinases. The encoded protein is a chromosomal passenger protein that forms complexes with Aurora-B and inner centromere proteins and may play a role in organizing microtubules in relation to centrosome/spindle function during mitosis. This gene is overexpressed in several cancer cell lines, suggesting an involvement in oncogenic signal transduction. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2008] |
| Alternative Names |
AURKC AIE 2 Aie1 AIE2 AIK 3 AIK3 ARK 3 ARK-3 ARK3 Aur C AurC Aurkc AURKC_HUMAN aurora 3 Aurora C Aurora kinase C aurora related kinase 3 Aurora-related kinase 3 Aurora/Ipl1 related kinase 3 Aurora/Ipl1-related kinase 3 Aurora/Ipl1/Eg2 protein 2 EC 2.7.11.1 Serine threonine protein kinase 13 serine/threonine kinase 13 (aurora/IPL1 like) serine/threonine protein kinase aurora C Serine/threonine-protein kinase 13 Serine/threonine-protein kinase aurora-C SPGF5 STK13 |
| Molecular Weight(MW) |
36 kDa |
| Cellular Localization |
Centromere,Chromosome,Cytoplasm,Cytoskeleton,Nucleus. |