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OM682709
Discount Price
OM682709-100ul
100ul
Product Profile
Product Name Anti-Phospho-MEKK1 (Thr1402) antibody
Antibody Type Primary Antibodies
Immunogen Synthetic peptide conjugated with KLH
Modification p-Thr1402
Key Feature
Clonality Polyclonal
Isotype IgG
Host Species Rabbit
Concentration 1mg/ml
Purification Affinity purified
Target Information
Gene Symbol MAP3K1
Gene Synonyms MEKK
MEKK1
SRXY6
MEKK 1
MAPKKK1
Gene Full Name mitogen-activated protein kinase kinase kinase 1
Gene Summary The protein encoded by this gene is a serine/threonine kinase and is part of some signal transduction cascades, including the ERK and JNK kinase pathways as well as the NF-kappa-B pathway. The encoded protein is activated by autophosphorylation and requires magnesium as a cofactor in phosphorylating other proteins. This protein has E3 ligase activity conferred by a plant homeodomain (PHD) in its N-terminus and phospho-kinase activity conferred by a kinase domain in its C-terminus. [provided by RefSeq, Mar 2012]
Alternative Names M3K1_HUMAN
MAP3K1
MAPK/ERK kinase kinase 1
MAPKKK1
MEK kinase 1
MEKK 1
Mekk
MEKK1
Mitogen activated protein kinase kinase kinase 1
Mitogen activated protein kinase kinase kinase 1
E3 ubiquitin protein ligase
Mitogen-activated protein kinase kinase kinase 1
SRXY6
Molecular Weight(MW) 164 kDa
Cellular Localization Cytosol, Tight junction
Database Links
SwissProt ID Q13233
Additional Information
Form Liquid
Storage Instructions Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle.
Storage Buffer Purified antibody in PBS with 0.05% sodium azide,40% Glycerol.
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